PDF(Pubmed)
Abstract：
Soil-transmitted helminths (STH) is a major healthcare challenge in the pediatric age group affecting poor and deprived parts of our community. The main species that infect people are roundworm (AL, Ascaris lumbricoides ), whipworm (TT, Trichuris trichiura ), and hookworms (HW, Ancylostoma duodenale and Necator americanus ). We aimed to estimate the pooled prevalence of STH infections in India in the pediatric age group (< 18 years) and assess the risk factors associated with STH in this age group. Three databases were searched (PubMed, Scopus, and Embase) up to February 16, 2021 with deliberate and inclusive search terms for original research articles estimating the prevalence of either of the three STH in India. Data extracted included individual prevalence of the three STH, prevalence of double or triple infections, and associated risk factors. We identified systematically 1,408 publications, of which 44 were included for the final analysis, including studies from 20 states covering 34,590 children. In our study, the prevalence of AL ranged from 0.8 to 91% with a pooled prevalence of 25%, prevalence of TT ranged from 0.3 to 72% with a pooled prevalence of 13%, and for HW prevalence ranged from 0.2 to 80% with pooled prevalence of 10%. Two most important risk factors with higher odds ratio were open defecation practices or open latrine (odds ratio: 5.2) and washing hands without soap using water only (odds ratio: 2.49). Knowledge of areas with high prevalence of STH and associated risk factors would help in designing effective control strategies in the high-risk groups to prevent infection and aid in a drastic reduction of morbidity in children.
摘要：
土壤传播的蠕虫（STH）是儿科年龄组的主要医疗保健挑战，影响我们社区的贫困和贫困部分。感染人的主要物种是蛔虫(AL，蛔虫)，鞭虫(TT,Trichuristrichiura），和钩虫(HW，十二指肠囊肿和美洲囊肿）。我们旨在评估印度儿童年龄组（<18岁）中STH感染的合并患病率，并评估该年龄组与STH相关的危险因素。搜索了三个数据库(PubMed，Scopus,和Embase）截至2021年2月16日，对原始研究文章进行深思熟虑和包容性的搜索，以估计印度三种STH中任何一种的患病率。提取的数据包括三种STH的个体患病率，双重或三重感染的患病率，和相关的危险因素。我们系统地确定了1,408种出版物，其中44个被列入最终分析，包括来自20个州的34,590名儿童的研究。在我们的研究中,AL的患病率范围为0.8％至91％，合并患病率为25％，TT的患病率范围为0.3％至72％，合并患病率为13％，HW的患病率为0.2％至80％，合并患病率为10％。赔率比较高的两个最重要的风险因素是开放式排便实践或开放式厕所（赔率比：5.2）和仅用水不使用肥皂洗手（赔率比：2.49）。了解STH流行率较高的地区及相关危险因素将有助于在高危人群中设计有效的控制策略，以预防感染并帮助大幅降低儿童发病率。
