关键词: Abstinence Alcohol Induced Alcohol Use Disorder Impotence India

Mesh : Male Humans Infant, Newborn Erectile Dysfunction / etiology Alcoholism / complications Follow-Up Studies Prospective Studies Ethanol Liver Diseases, Alcoholic

来  源:   DOI:10.1016/j.jsxm.2022.01.517

Abstract:
There is a compelling evidence for the relation between alcohol use and erectile dysfunction (ED), however the impact of alcohol abstinence on improvement of ED is explored sparsely.
This study aimed to determine the impact of alcohol abstinence on ED. The association between total duration of drinking, the quantity of alcohol consumed, sociodemographic, clinical variables and ED were also studied.
One hundred and four subjects with alcohol use disorder and complaints of ED meeting the inclusion and exclusion criteria were recruited into the study after taking written informed consent. The subjects were assessed at baseline and after 3 months of abstinence from alcohol with IIEF-5 and a specially designed pro forma. Wilcoxon signed rank test was used to assess the change in ED after 3 months of abstinence. Chi square test was done to assess the associations and binary logistic regression was done to determine the significance of variables after 3 months of abstinence.
Improvement in ED after 3 months of abstinence from alcohol and its association between socio demographic and clinical variables were assessed.
Of the 104 subjects studied, 88.5% (92) showed improvement in ED after 3 months of abstinence from alcohol. Wilcoxon signed rank test showed that the improvement in ED after 3 months of abstinence was significant. (Z = 8.708, P < .001). Significant association was found between age, alcoholic liver disease, total duration of drinking, and number of standard drinks per day with ED after 3 months of abstinence.
Information that ED will improve with abstinence from alcohol can be used in deaddiction treatment to provide a motivation for change.
This study aims to fill the gap in literature as only a few studies have examined the impact of abstinence from alcohol on ED. The main limitations of this study are short follow up period and since this study was conducted in a tertiary care hospital it could have given rise to Berksonian bias.
Results indicate that ED shows improvement with abstinence from alcohol. Absence of alcoholic liver disease, younger age, shorter duration of drinking, lesser number of standard drinks per day had a significant influence in the improvement of ED with alcohol abstinence and this information can be beneficial in treatment to provide an impetus for change.
摘要:
背景:有令人信服的证据表明饮酒与勃起功能障碍(ED)之间的关系,然而,对酒精戒断对ED改善的影响进行了研究。
目的:本研究旨在确定戒酒对ED的影响。饮酒总持续时间之间的关联,消耗的酒精量,社会人口统计学,还研究了临床变量和ED。
方法:在接受书面知情同意书后,招募了104名患有酒精使用障碍和ED的受试者,这些受试者符合纳入和排除标准。使用IIEF-5和专门设计的备考,在基线和戒酒3个月后对受试者进行评估。使用Wilcoxon符号秩检验评估禁欲3个月后ED的变化。进行卡方检验以评估相关性,并进行二元逻辑回归以确定禁欲3个月后变量的显著性。
结果:评估了戒酒3个月后ED的改善及其在社会人口统计学和临床变量之间的关联。
结果:在研究的104个受试者中,戒酒3个月后,88.5%(92)的ED有所改善。Wilcoxon符号秩检验显示,禁欲3个月后ED的改善显着。(Z=8.708,P<.001)。发现年龄之间存在显著关联,酒精性肝病,饮酒的总持续时间,以及禁欲3个月后每天使用ED的标准饮料数量。
结论:关于戒酒会改善ED的信息可用于戒酒治疗,以提供改变的动力。
这项研究旨在填补文献中的空白,因为只有少数研究检查了戒酒对ED的影响。这项研究的主要局限性是随访期短,并且由于这项研究是在三级保健医院进行的,因此可能会引起Berksonian偏见。
结论:结果表明,戒除酒精后,ED有所改善。没有酒精性肝病,年龄较小,饮酒时间较短,每天较少数量的标准饮料对酒精戒断的ED改善有显著影响,这些信息对治疗有益,为改变提供动力.
公众号