关键词: covid-19 deep vein thrombosis pulmonary embolism thromboprophylaxis venous thromboembolism

来  源:   DOI:10.7759/cureus.36009   PDF(Pubmed)

Abstract:
The recent coronavirus disease 2019 (COVID-19) pandemic has worse medical consequences, especially when affecting people with comorbidities such as diabetes, lung disease, hypertension, burn and trauma. The pathophysiology of COVID-19 infection includes thromboembolic events that were described in previous studies as a risk of venous thromboembolism (VTE). This risk is higher in burn patients, especially in the electrical type, which is generally attributed to their hypercoagulable state. This article reviews a detailed history, examination, and investigations of a 38-year-old male hospitalized burn patient with COVID-19 infection. Although on chemical thromboembolic prophylaxis, the patient developed extensive pulmonary embolism (PE) and, more interestingly, had atypical PE signs and symptoms. The present case aims to develop a special venous thromboembolism prophylaxis protocol between prophylactic and therapeutic dosages for COVID-19 burn patients.
摘要:
最近的2019年冠状病毒病(COVID-19)大流行带来了更糟糕的医疗后果,尤其是影响糖尿病等合并症患者时,肺部疾病,高血压,烧伤和外伤.COVID-19感染的病理生理学包括血栓栓塞事件,以前的研究将其描述为静脉血栓栓塞(VTE)的风险。烧伤患者的风险更高,尤其是在电气类型中,这通常归因于他们的高凝状态。这篇文章回顾了详细的历史,考试,并调查了一名38岁男性住院烧伤患者的COVID-19感染。尽管在化学血栓栓塞预防方面,患者出现广泛的肺栓塞(PE),更有趣的是,有不典型的PE体征和症状。本病例旨在为COVID-19烧伤患者制定预防和治疗剂量之间的特殊静脉血栓栓塞预防方案。
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