Abstract:
A 63-year-old man presenting with peripheral neuropathies was diagnosed of Waldenström\'s macroglobulinemia, and Bing-Neel syndrome was subsequently confirmed via cerebrospinal fluid examinations. Besides involvement in bone marrow, lymph nodes, as well as the thoracic and sacral nerve root, 68Ga-Pentixafor PET/CT detected active tracer uptake in bilateral choroid plexus, which was negative in 18F-FDG PET/CT, possibly suggesting the involvement of Bing-Neel syndrome. The coexisting pituitary macroadenoma was FDG-avid but negative in 68Ga-Pentixafor PET/CT. After six cycles of chemotherapy, the follow-up PET/CT showed complete remission of the previous disease, including the high uptake of 68Ga-Pentixafor in choroid plexus. However, the hypermetabolic pituitary macroadenoma remained unchanged.
摘要:
一名63岁的患有周围神经病变的男子被诊断为Waldenström巨球蛋白血症,随后通过脑脊液检查证实了Bing-Neel综合征。除了涉及骨髓,淋巴结,以及胸和骶神经根,68Ga-PentixaforPET/CT检测到双侧脉络丛中的示踪剂摄取活跃,18F-FDGPET/CT为阴性,这可能暗示了Bing-Neel综合征的参与.共存的垂体大腺瘤是FDG-aid,但在68Ga-Pentixa的PET/CT中阴性。经过六个周期的化疗,随访PET/CT显示先前疾病完全缓解,包括脉络丛中68Ga-Pentixafor的高摄取。然而,高代谢性垂体大腺瘤保持不变。