PDF(Pubmed)
Abstract：
UNASSIGNED: Post ablative oral mucosal defect resulting from the removal of tumors can be treated with various techniques.
UNASSIGNED: In this paper, we are showing what, in our experience, are the advantages and disadvantages given using biosynthetic skin substitutes when dealing with this kind of lesions.
UNASSIGNED: Patients included in the sample came to our attention with both neoplastic lesions (11 subjects) and important scar retraction after previous oncologic surgery (1 subject). All patients underwent trans-oral resection surgery following the same surgical protocol and post ablative oral mucosal defect were treated using the dermal regeneration template. The surgical defect location, size, and time of removal of the silicone layer varied from one subject to the other.
UNASSIGNED: Most patients showed good healing with reduced scarring and adequate remucosalisation of the defect. The main complications were shown in a palatal lesion treated with concomitant osteal resection, which developed an oroantral fistula at follow up, and tongue lesions which showed some scarring.
UNASSIGNED: Given our experience, we would advise using dermal substitutes when reconstructing oral defects only after a cautious evaluation of the area of the lesion, the gap size, the possible adherence of the membrane to the gap, and the presence of tissue supporting the overlying membrane.
UNASSIGNED: In this paper, we are showing what, in our experience, are the advantages and disadvantages given using biosynthetic skin substitutes when dealing with this kind of lesions.
UNASSIGNED: Patients included in the sample came to our attention with both neoplastic lesions (11 subjects) and important scar retraction after previous oncologic surgery (1 subject). All patients underwent trans-oral resection surgery following the same surgical protocol and post ablative oral mucosal defect were treated using the dermal regeneration template. The surgical defect location, size, and time of removal of the silicone layer varied from one subject to the other.
UNASSIGNED: Most patients showed good healing with reduced scarring and adequate remucosalisation of the defect. The main complications were shown in a palatal lesion treated with concomitant osteal resection, which developed an oroantral fistula at follow up, and tongue lesions which showed some scarring.
UNASSIGNED: Given our experience, we would advise using dermal substitutes when reconstructing oral defects only after a cautious evaluation of the area of the lesion, the gap size, the possible adherence of the membrane to the gap, and the presence of tissue supporting the overlying membrane.
摘要：
■由于切除肿瘤而导致的消融后口腔粘膜缺损可用各种技术治疗。
■在本文中，我们展示了什么，根据我们的经验,在处理这种病变时，使用生物合成皮肤替代品的优点和缺点。
■我们注意到样本中包含的患者既有肿瘤性病变（11名受试者），也有先前肿瘤手术后的重要疤痕回缩（1名受试者）。所有患者均按照相同的手术方案进行经口切除手术，并使用真皮再生模板治疗消融后口腔粘膜缺损。手术缺损的位置,尺寸,和除去硅氧烷层的时间从一个对象到另一个对象不同。
■大多数患者表现出良好的愈合，减少了瘢痕形成和足够的修复缺损。主要并发症表现为伴随骨切除术治疗的pal骨病变，在随访中出现了口窦瘘，和舌头上有疤痕的病变.
■鉴于我们的经验，只有在对病变区域进行谨慎评估后，我们才建议在重建口腔缺损时使用真皮替代品，间隙大小,膜可能附着在间隙上，以及支持覆盖膜的组织的存在。
■在本文中，我们展示了什么，根据我们的经验,在处理这种病变时，使用生物合成皮肤替代品的优点和缺点。
■我们注意到样本中包含的患者既有肿瘤性病变（11名受试者），也有先前肿瘤手术后的重要疤痕回缩（1名受试者）。所有患者均按照相同的手术方案进行经口切除手术，并使用真皮再生模板治疗消融后口腔粘膜缺损。手术缺损的位置,尺寸,和除去硅氧烷层的时间从一个对象到另一个对象不同。
■大多数患者表现出良好的愈合，减少了瘢痕形成和足够的修复缺损。主要并发症表现为伴随骨切除术治疗的pal骨病变，在随访中出现了口窦瘘，和舌头上有疤痕的病变.
■鉴于我们的经验，只有在对病变区域进行谨慎评估后，我们才建议在重建口腔缺损时使用真皮替代品，间隙大小,膜可能附着在间隙上，以及支持覆盖膜的组织的存在。
