Abstract：
About 5-10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women\'s subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants.
An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables.
660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP.
Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help.
An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables.
660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP.
Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help.
摘要：
大约5-10%的乳腺癌病例归因于基因突变。对有基因突变的女性进行预防性干预，基因筛查BRCA测试最近在伊朗实施。本研究旨在确定伊朗妇女对早期发现乳腺癌的BRCA筛查测试的主观评价，以帮助决策者做出有关乳腺癌基因筛查测试的决定，并了解申请人。
德黑兰30岁以上的女性完成了一项在线调查，2021年伊朗首都。定义了关于乳腺癌遗传筛查测试的假设方案。通过支付卡使用或有估值方法（CVM）通过支付意愿（WTP）评估测试的主观估值。人口统计,乳腺癌病史,知识,生理变量被认为是独立变量，逻辑回归模型评估了WTP与变量之间的关系。
其中包括660名女性。88％的参与者打算参加BRCA乳腺癌基因筛查，如果它是免费的。测试的平均WTP约为20美元。基于逻辑回归，收入,乳腺癌或卵巢癌家族史，积极的态度与WTP相关。
伊朗妇女愿意进行基因筛查BRCA测试，并为此付费。本研究的结果对于政策制定者在BRCA基因筛查测试的资助和确定共同支付方面非常重要。为了实现女性在乳腺癌筛查计划中的高参与率，积极的态度应该作为一种心理因素。教育和信息计划可以帮助。
德黑兰30岁以上的女性完成了一项在线调查，2021年伊朗首都。定义了关于乳腺癌遗传筛查测试的假设方案。通过支付卡使用或有估值方法（CVM）通过支付意愿（WTP）评估测试的主观估值。人口统计,乳腺癌病史,知识,生理变量被认为是独立变量，逻辑回归模型评估了WTP与变量之间的关系。
其中包括660名女性。88％的参与者打算参加BRCA乳腺癌基因筛查，如果它是免费的。测试的平均WTP约为20美元。基于逻辑回归，收入,乳腺癌或卵巢癌家族史，积极的态度与WTP相关。
伊朗妇女愿意进行基因筛查BRCA测试，并为此付费。本研究的结果对于政策制定者在BRCA基因筛查测试的资助和确定共同支付方面非常重要。为了实现女性在乳腺癌筛查计划中的高参与率，积极的态度应该作为一种心理因素。教育和信息计划可以帮助。
