关键词: Bietti crystalline dystrophy macula macular neovascularization optical coherence tomography optical coherence tomography angiography

来  源:   DOI:10.3205/oc000214   PDF(Pubmed)

Abstract:
UNASSIGNED: To report the successful outcome with a single intravitreal ranibizumab injection in a 15-year-old boy with Bietti crystalline dystrophy (BCD) who developed a unilateral macular neovascularization (MNV).
UNASSIGNED: A retrospective case report.
UNASSIGNED: A 15-year-old Caucasian boy with Bietti crystalline dystrophy was diagnosed to have a unilateral MNV a year after the initial examination with the help of multimodal imaging and he was treated with a single intravitreal ranibizumab injection. Five months later, visual acuity improved and anatomically a dry-looking macula was noted.
UNASSIGNED: MNV is among the rare macular complications of BCD. The present case is the third reported pediatric case with MNV in association with BCD and the first pediatric BCD patient who received a vascular endothelial growth factor inhibitor (anti-VEGF) agent.
摘要:
报告在患有Bietti晶体营养不良(BCD)的15岁男孩中单次玻璃体内注射雷珠单抗的成功结果,该男孩发展为单侧黄斑新生血管(MNV)。
回顾性病例报告。
一名15岁的白种人男孩患有Bietti晶体营养不良,在多模态成像的帮助下,在初次检查后一年被诊断为单侧MNV,并接受了单次玻璃体内雷珠单抗注射治疗。五个月后,视力改善,在解剖学上注意到黄斑干燥。
MNV是BCD的罕见黄斑并发症之一。本病例是第三例报道的MNV与BCD相关的儿科病例,也是第一位接受血管内皮生长因子抑制剂(抗VEGF)药物的儿科BCD患者。
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