关键词: M. odoratimimus Myroides odoratimimus immunocompetent host intracranial infection tigecycline

来  源:   DOI:10.2147/IDR.S403088   PDF(Pubmed)

Abstract:
Intracranial infections are the most serious and common postoperative complications with significant mortality and morbidity. Myroides odoratimimus (M. odoratimimus), a Gram-negative environmental species and an opportunistic microorganism, predominantly infects immunocompromised individuals. Limited clinical experiences and documented multidrug resistance have resulted in a scarcity of data on the treatment of M. odoratimimus infections. As far as we know, this is the first reported case of an intracranial M. odoratimimus infection with external ventricular drains (EVD) that was effectively treated with a combination of intravenous and intraventricular tigecycline in an immunocompetent adult host.
摘要:
颅内感染是最严重和常见的术后并发症,具有显著的死亡率和发病率。Myroidesodoratimimus(M.odoratimimus),革兰氏阴性环境物种和机会微生物,主要感染免疫功能低下的个体。有限的临床经验和所记录的多药耐药性导致了关于多药多菌感染治疗的数据的匮乏。据我们所知,这是第一例报道的颅内多毛分枝杆菌感染伴外部脑室引流(EVD)的病例,该病例在有免疫能力的成年宿主中通过静脉和心室内替加环素的联合治疗得到了有效治疗.
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