PDF(Pubmed)
Abstract：
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus (SFTSV), which has a high fatality rate. This disease has become increasingly prevalent in recent years in Jiangsu province, with a noticeable rise in its incidence. Notably, fatal cases have also been increasing. Our study aimed to analyze the epidemiological characteristics and risk factors associated with the fatal cases of SFTS in Jiangsu province from 2011 to September 2022.
A retrospective study was performed among 698 SFTS cases during 2011-2022 in Jiangsu Province, China. Cox regression analyses were used to determine the dependent and independent risk factors that affected patient survival time. ArcGIS 10.7 was used for the visualization of the geographical distribution of the deaths from SFTS.
There were 698 SFTS cases reported, with an increasing incidence, over the 12-year period. Among these cases, 43 deaths were reported. Fatal cases of SFTS were reported in 12 district counties from 2011 to 2022. Notably, most of the deaths occurred in Lishui county of Nanjing City. The median age of those who died was 69 years, with age ranges from 50 to 83 years. Multivariable Cox regression analysis showed that older age (>70) and living in Lishui county were risk factors for death from SFTS in Jiangsu province. Therefore, older adults aged over 70 years and residing in Lishui county were the high-risk group for SFTS mortality.
Over the past 12 years, we have observed a consistent rise in the incidence of SFTS, accompanied by a relatively high case fatality rate, making it a critical public health issue. Therefore, it is urgently necessary to study the impact of meteorological factors on SFTS epidemics and devise prevention and control strategies.
A retrospective study was performed among 698 SFTS cases during 2011-2022 in Jiangsu Province, China. Cox regression analyses were used to determine the dependent and independent risk factors that affected patient survival time. ArcGIS 10.7 was used for the visualization of the geographical distribution of the deaths from SFTS.
There were 698 SFTS cases reported, with an increasing incidence, over the 12-year period. Among these cases, 43 deaths were reported. Fatal cases of SFTS were reported in 12 district counties from 2011 to 2022. Notably, most of the deaths occurred in Lishui county of Nanjing City. The median age of those who died was 69 years, with age ranges from 50 to 83 years. Multivariable Cox regression analysis showed that older age (>70) and living in Lishui county were risk factors for death from SFTS in Jiangsu province. Therefore, older adults aged over 70 years and residing in Lishui county were the high-risk group for SFTS mortality.
Over the past 12 years, we have observed a consistent rise in the incidence of SFTS, accompanied by a relatively high case fatality rate, making it a critical public health issue. Therefore, it is urgently necessary to study the impact of meteorological factors on SFTS epidemics and devise prevention and control strategies.
摘要：
■严重发热伴血小板减少综合征（SFTS）是由SFTS病毒（SFTSV）引起的一种新兴传染病，死亡率很高。近年来,该病在江苏省日益流行,发病率明显增加。值得注意的是,致命病例也在增加。分析2011-2022年9月江苏省SFTS死亡病例的流行病学特征及相关危险因素。
■对2011-2022年江苏省698例SFTS病例进行了回顾性研究，中国。Cox回归分析用于确定影响患者生存时间的依赖和独立危险因素。ArcGIS10.7用于可视化SFTS死亡的地理分布。
■报告了698例SFTS，随着发病率的增加，在12年期间。在这些案例中,报告有43人死亡。2011年至2022年，12个区县报告了SFTS的致命病例。值得注意的是,大部分死亡发生在南京市丽水县。死者的平均年龄是69岁,年龄从50到83岁不等。多因素Cox回归分析显示,年龄大于70岁、居住在丽水县是江苏省SFTS死亡的危险因素。因此,70岁以上居住在丽水县的老年人是SFTS死亡率的高危人群.
■在过去的12年里，我们观察到SFTS的发病率持续上升，伴随着相对较高的病死率，使其成为一个关键的公共卫生问题。因此,迫切需要研究气象因素对SFTS流行的影响，并制定预防和控制策略。
■对2011-2022年江苏省698例SFTS病例进行了回顾性研究，中国。Cox回归分析用于确定影响患者生存时间的依赖和独立危险因素。ArcGIS10.7用于可视化SFTS死亡的地理分布。
■报告了698例SFTS，随着发病率的增加，在12年期间。在这些案例中,报告有43人死亡。2011年至2022年，12个区县报告了SFTS的致命病例。值得注意的是,大部分死亡发生在南京市丽水县。死者的平均年龄是69岁,年龄从50到83岁不等。多因素Cox回归分析显示,年龄大于70岁、居住在丽水县是江苏省SFTS死亡的危险因素。因此,70岁以上居住在丽水县的老年人是SFTS死亡率的高危人群.
■在过去的12年里，我们观察到SFTS的发病率持续上升，伴随着相对较高的病死率，使其成为一个关键的公共卫生问题。因此,迫切需要研究气象因素对SFTS流行的影响，并制定预防和控制策略。
