Abstract:
The uterine artery pulsatility index (PI) assessed by Doppler ultrasound reflects the impedance to the blood flow in the vessel distal to the sampling point. We aimed to assess the accuracy of the uterine artery PI for the diagnosis of puberty in girls. A PRISMA-ScR-compliant scoping review was performed in the MEDLINE and Embase databases with the search terms \"puberty\" and \"Doppler ultrasonography\". Studies that included girls aged 0-18 years who underwent pelvic Doppler ultrasound with calculation of uterine artery PI were eligible. Ten studies comprising 1385 girls aged 1.2-18 years were included. The selected studies included participants from Italy, Brazil, Iran, Belgium and Denmark, and were published between 1996 and 2021. Six studies selected girls who were referred for evaluation of pubertal disorders, while four studies included only healthy girls. Nine studies found a significant difference in Doppler signal pattern and PI according to pubertal stage, with PI cutoff points ranging from 2.5 to 4.6 for the diagnosis of puberty, with a sensitivity of 77%-94%, specificity of 85%-100%, and accuracy of 79%-98%. Doppler assessment of the uterine arteries with PI calculation is a useful noninvasive tool in the diagnosis of pubertal onset in girls.
摘要:
通过多普勒超声评估的子宫动脉搏动指数(PI)反映了对采样点远端血管中血流的阻抗。我们旨在评估子宫动脉PI诊断女孩青春期的准确性。在MEDLINE和Embase数据库中进行了符合PRISMA-ScR标准的范围审查,检索词为“青春期”和“多普勒超声检查”。纳入0-18岁女孩接受盆腔多普勒超声检查并计算子宫动脉PI的研究合格。包括10项研究,包括1385名1.2-18岁的女孩。选定的研究包括来自意大利的参与者,巴西,伊朗,比利时和丹麦,并在1996年至2021年之间出版。六项研究选择了被转诊为青春期障碍评估的女孩,而四项研究只包括健康女孩。九项研究发现,根据青春期阶段,多普勒信号模式和PI存在显着差异,用于诊断青春期的PI截止点在2.5到4.6之间,灵敏度为77%-94%,特异性为85%-100%,准确率为79%-98%。通过PI计算对子宫动脉进行多普勒评估是诊断女孩青春期发作的有用的无创工具。