Abstract：
The incidence of two synchronous carcinomas originating from the uterine corpus and uterine cervix, both endometrioid subtypes, is exceedingly rare. Herein, we presented synchronous early stage G1 adenocarcinoma of the uterine corpus with cervical G2 endometrioid adenocarcinoma. Although both neoplasms displayed the same histological subtype, they differed significantly according to the histological grading or clinical stage of the disease. Finally, it is worth emphasizing that both tumors were preceded by different precancerous lesions, atypical endometrial hyperplasia (AEH) and foci of endometriosis localized within the uterine cervix. Although AEH is a well-known precancerous condition of endometrioid carcinoma, the mechanisms resulting in the malignant transformation of endometriosis foci to the cervical endometrioid carcinoma are still a matter of controversy. We briefly summarized the impact of different precancerous lesions on the development of synchronous female genital tract neoplasms with the same histotype.
摘要：
两种源于子宫体和子宫颈的同步癌的发生率，子宫内膜样亚型,非常罕见。在这里，我们提出了子宫体的早期G1期腺癌与宫颈G2子宫内膜样腺癌的同步。尽管两种肿瘤都表现出相同的组织学亚型，根据疾病的组织学分级或临床阶段，它们存在显着差异。最后,值得强调的是，两种肿瘤之前都有不同的癌前病变，不典型的子宫内膜增生（AEH）和位于子宫颈内的子宫内膜异位症病灶。尽管AEH是众所周知的子宫内膜样癌的癌前病变，子宫内膜异位症病灶恶性转化为宫颈子宫内膜样癌的机制仍存在争议。我们简要总结了不同癌前病变对具有相同组织型的同步女性生殖道肿瘤发展的影响。
