Abstract:
The growing prevalence of nonalcoholic fatty liver disease (NAFLD) has sparked interest in understanding genetics and epigenetics associated with the development and progression of the disease. A better understanding of the genetic factors related to progression will be beneficial in the risk stratification of patients. These genetic markers can also serve as potential therapeutic targets in the future. In this review, we focus on the genetic markers associated with the progression and severity of NAFLD.
摘要:
非酒精性脂肪性肝病(NAFLD)的患病率越来越高,引起了人们对理解与该疾病的发展和进展相关的遗传学和表观遗传学的兴趣。更好地了解与进展相关的遗传因素将有利于患者的风险分层。这些遗传标记也可以作为未来的潜在治疗靶标。在这次审查中,我们关注与NAFLD进展和严重程度相关的遗传标记.