关键词: Adrenal adrenalectomy large cell neuroendocrine carcinoma metachronous solitary metastasis tumor size

Mesh : Male Humans Aged Stomach Neoplasms / surgery pathology Adenocarcinoma / surgery pathology Carcinoma, Neuroendocrine / surgery Adrenalectomy Adrenal Gland Neoplasms / surgery diagnosis

来  源:   DOI:10.1177/03000605231163709

Abstract:
Surgical resection is rarely employed for the treatment of metastatic gastric cancer, especially in patients with adrenal metastases, which usually indicate advanced systemic dissemination. Few published case reports have thus described the use of adrenalectomy for adrenal metastases from gastric cancer. In addition, most primary gastric malignancies are gastric adenocarcinomas, and gastric large cell neuroendocrine carcinoma (GLCNEC) is less common and has a poor prognosis. We report the case of a 71-year-old man who was diagnosed with solitary adrenal metastases 10 months after radical resection for GLCNEC and who was treated by adrenalectomy. He was followed-up for 9 months after adrenalectomy, with no further evidence of disease at his last follow-up examination. This case indicates that elective surgical resection may be feasible, even in rare cases of GLCNEC metastases to the adrenal glands, provided that the patient meets certain criteria, including solitary, metachronous tumors less than 4 cm.
摘要:
手术切除很少用于治疗转移性胃癌,尤其是肾上腺转移患者,这通常表明先进的系统传播。因此,很少有公开的病例报告描述了肾上腺切除术治疗胃癌肾上腺转移的用途。此外,大多数原发性胃恶性肿瘤是胃腺癌,胃大细胞神经内分泌癌(GLCNEC)较少见,预后较差。我们报告了一例71岁的男子,该男子在接受GLCNEC根治性切除术后10个月被诊断为孤立性肾上腺转移,并接受了肾上腺切除术。他在肾上腺切除术后随访了9个月,在他的最后一次随访检查中没有进一步的疾病证据。这种情况表明选择性手术切除可能是可行的,即使在罕见的GLCNEC转移到肾上腺的病例中,如果患者符合某些标准,包括孤独,异时肿瘤小于4厘米。
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