Abstract：
OBJECTIVE: To analyze BE on ABUS using BI-RADS and a modified classification in association with mammographic density and clinical features.
METHODS: Menopausal status, parity, and family history of breast cancer were collected for 496 women who underwent ABUS and mammography. Three radiologists independently reviewed all ABUS BE and mammographic density. Statistical analyses including kappa statistics (κ) for interobserver agreement, Fisher\'s exact test, and univariate and multivariate multinomial logistic regression were performed.
RESULTS: BE distribution between the two classifications and between each classification and mammographic density were associated (P < 0.001). BI-RADS homogeneous-fibroglandular (76.8%) and modified heterogeneous BE (71.3%, 75.7%, and 87.5% of mild, moderate, and marked heterogeneous background echotexture, respectively) tended to be dense. BE was correlated between BI-RADS homogeneous-fat and modified homogeneous background (95.1%) and between BI-RADS homogeneous-fibroglandular or heterogeneous (90.6%) and modified heterogeneous (86.9%) (P < 0.001). In multinomial logistic regression, age < 50 years was independently associated with heterogeneous BE (OR, 8.89, P = 0.003, in BI-RADS; OR, 3.74; P = 0.020 in modified classification).
CONCLUSIONS: BI-RADS homogeneous-fat and modified homogeneous BE on ABUS was likely to be mammographically fatty. However, BI-RADS homogeneous-fibroglandular or heterogeneous BE might be classified as any modified BE. Younger age was independently associated with heterogeneous BE.
METHODS: Menopausal status, parity, and family history of breast cancer were collected for 496 women who underwent ABUS and mammography. Three radiologists independently reviewed all ABUS BE and mammographic density. Statistical analyses including kappa statistics (κ) for interobserver agreement, Fisher\'s exact test, and univariate and multivariate multinomial logistic regression were performed.
RESULTS: BE distribution between the two classifications and between each classification and mammographic density were associated (P < 0.001). BI-RADS homogeneous-fibroglandular (76.8%) and modified heterogeneous BE (71.3%, 75.7%, and 87.5% of mild, moderate, and marked heterogeneous background echotexture, respectively) tended to be dense. BE was correlated between BI-RADS homogeneous-fat and modified homogeneous background (95.1%) and between BI-RADS homogeneous-fibroglandular or heterogeneous (90.6%) and modified heterogeneous (86.9%) (P < 0.001). In multinomial logistic regression, age < 50 years was independently associated with heterogeneous BE (OR, 8.89, P = 0.003, in BI-RADS; OR, 3.74; P = 0.020 in modified classification).
CONCLUSIONS: BI-RADS homogeneous-fat and modified homogeneous BE on ABUS was likely to be mammographically fatty. However, BI-RADS homogeneous-fibroglandular or heterogeneous BE might be classified as any modified BE. Younger age was independently associated with heterogeneous BE.
摘要：
目的：使用BI-RADS分析ABUS的BE，并结合乳腺密度和临床特征进行改良分类。
方法：绝经状态，奇偶校验，我们收集了496名接受ABUS和乳房X线照相术的女性的乳腺癌家族史.三名放射科医生独立检查了所有ABUSBE和乳房X线摄影密度。包括卡帕统计(κ)在内的统计分析，用于观察者之间的协议，费希尔的精确检验，并进行了单变量和多变量多项逻辑回归。
结果：两种分类之间以及每种分类之间的BE分布与乳腺摄影密度相关（P<0.001）。BI-RADS均匀-纤维腺体（76.8％）和修饰的异质BE（71.3％，75.7%,87.5%的轻度，中度,和明显的异质背景回声结构，分别)倾向于密集。BE在BI-RADS均质脂肪和改良均质背景（95.1％）之间以及BI-RADS均质纤维腺体或异质（90.6％）与改良异质（86.9％）之间相关（P<0.001）。在多项逻辑回归中，年龄<50岁与异质性BE(OR，8.89，P=0.003，在BI-RADS中；或，3.74；修改后的分类中P=0.020）。
结论：ABUS上的BI-RADS均质脂肪和改良均质BE可能是乳房X线检查的脂肪。然而,BI-RADS均质-纤维腺体或异质BE可归类为任何修饰的BE。年龄较小与异质性BE独立相关。
方法：绝经状态，奇偶校验，我们收集了496名接受ABUS和乳房X线照相术的女性的乳腺癌家族史.三名放射科医生独立检查了所有ABUSBE和乳房X线摄影密度。包括卡帕统计(κ)在内的统计分析，用于观察者之间的协议，费希尔的精确检验，并进行了单变量和多变量多项逻辑回归。
结果：两种分类之间以及每种分类之间的BE分布与乳腺摄影密度相关（P<0.001）。BI-RADS均匀-纤维腺体（76.8％）和修饰的异质BE（71.3％，75.7%,87.5%的轻度，中度,和明显的异质背景回声结构，分别)倾向于密集。BE在BI-RADS均质脂肪和改良均质背景（95.1％）之间以及BI-RADS均质纤维腺体或异质（90.6％）与改良异质（86.9％）之间相关（P<0.001）。在多项逻辑回归中，年龄<50岁与异质性BE(OR，8.89，P=0.003，在BI-RADS中；或，3.74；修改后的分类中P=0.020）。
结论：ABUS上的BI-RADS均质脂肪和改良均质BE可能是乳房X线检查的脂肪。然而,BI-RADS均质-纤维腺体或异质BE可归类为任何修饰的BE。年龄较小与异质性BE独立相关。
