PDF(Pubmed)
Abstract：
UNASSIGNED: Emphysematous osteomyelitis (EO) is an uncommon and deadly pathology characterized by occurrence of intraosseus air within the bone. However, only few of them have been reported. The use of local antibiotic delivery system has proven to be very effective in bone and joint infections as they offer decreased hospital stay and early clearance of infection. To the best of our knowledge, there are no reports on local antibiotic delivery using absorbable synthetic calcium sulfate beads in EO.
UNASSIGNED: A 59-year-old male with Type II diabetes mellitus, chronic kidney, and liver disease came with pain and swelling over left leg. After blood investigations and radiological evaluation, he was diagnosed to have EO of tibia with unknown source of infection. We successfully treated him with immediate surgical decompression and application of antibiotic impregnated absorbable calcium sulfate beads locally for improved local antibiotic delivery. Following this, he was further treated with culture sensitive intravenous antibiotics and his symptoms resolved.
UNASSIGNED: Early diagnosis and aggressive surgical intervention along with local antimicrobial therapy using calcium sulfate beads can offer better outcome in EO. The local antibiotic delivery system can decrease the use of prolonged intravenous antibiotic therapy and long hospital stay.
UNASSIGNED: A 59-year-old male with Type II diabetes mellitus, chronic kidney, and liver disease came with pain and swelling over left leg. After blood investigations and radiological evaluation, he was diagnosed to have EO of tibia with unknown source of infection. We successfully treated him with immediate surgical decompression and application of antibiotic impregnated absorbable calcium sulfate beads locally for improved local antibiotic delivery. Following this, he was further treated with culture sensitive intravenous antibiotics and his symptoms resolved.
UNASSIGNED: Early diagnosis and aggressive surgical intervention along with local antimicrobial therapy using calcium sulfate beads can offer better outcome in EO. The local antibiotic delivery system can decrease the use of prolonged intravenous antibiotic therapy and long hospital stay.
摘要：
■肺气肿性骨髓炎（EO）是一种罕见且致命的病理，其特征在于骨内出现骨内空气。然而,只有少数人被报道。局部抗生素递送系统的使用已被证明在骨和关节感染中非常有效,因为它们提供减少的住院时间和感染的早期清除。据我们所知,没有关于在EO中使用可吸收的合成硫酸钙珠进行局部抗生素递送的报道。
■一名59岁男性患有II型糖尿病，慢性肾脏，肝脏疾病伴随着左腿疼痛和肿胀。经过血液调查和放射学评估，他被诊断为胫骨EO，感染来源不明。我们通过立即手术减压和局部应用抗生素浸渍的可吸收硫酸钙珠成功治疗了他，以改善局部抗生素的输送。在此之后,他进一步接受了培养敏感的静脉抗生素治疗，症状得到了缓解。
■早期诊断和积极的手术干预以及使用硫酸钙珠的局部抗菌治疗可以提供更好的EO结果。局部抗生素递送系统可以减少长期静脉抗生素治疗的使用和长期住院。
■一名59岁男性患有II型糖尿病，慢性肾脏，肝脏疾病伴随着左腿疼痛和肿胀。经过血液调查和放射学评估，他被诊断为胫骨EO，感染来源不明。我们通过立即手术减压和局部应用抗生素浸渍的可吸收硫酸钙珠成功治疗了他，以改善局部抗生素的输送。在此之后,他进一步接受了培养敏感的静脉抗生素治疗，症状得到了缓解。
■早期诊断和积极的手术干预以及使用硫酸钙珠的局部抗菌治疗可以提供更好的EO结果。局部抗生素递送系统可以减少长期静脉抗生素治疗的使用和长期住院。
