PDF(Pubmed)
Abstract：
UNASSIGNED: This work aims to report the challenging diagnosis, treatment, and follow-up of a patient with persistent fetal vasculature (PFV) and retinoblastoma (RB).
UNASSIGNED: A 22-month-old boy presented with unilateral RB stage VB in the right eye and PFV in both eyes. The patient was treated with transpupillary laser ablation and systemic chemotherapy.
UNASSIGNED: Treatment resulted in complete tumor regression. Two years after the last systemic chemotherapy treatment, magnetic resonance imaging (MRI) showed increased signal intensity with progressive optic nerve enhancement, where intraneural malignancy could not be excluded. Enucleation of the right eye was performed. Histopathologic review showed no residual active malignancy in the enucleated globe.
UNASSIGNED: This case demonstrates the importance of a thorough clinical examination to establish the correct diagnosis and to rule out RB before any surgery. This case also highlights the importance of regular follow-ups after tumor regression with full a ophthalmologic examination, B-scan, and periodic MRI.
UNASSIGNED: A 22-month-old boy presented with unilateral RB stage VB in the right eye and PFV in both eyes. The patient was treated with transpupillary laser ablation and systemic chemotherapy.
UNASSIGNED: Treatment resulted in complete tumor regression. Two years after the last systemic chemotherapy treatment, magnetic resonance imaging (MRI) showed increased signal intensity with progressive optic nerve enhancement, where intraneural malignancy could not be excluded. Enucleation of the right eye was performed. Histopathologic review showed no residual active malignancy in the enucleated globe.
UNASSIGNED: This case demonstrates the importance of a thorough clinical examination to establish the correct diagnosis and to rule out RB before any surgery. This case also highlights the importance of regular follow-ups after tumor regression with full a ophthalmologic examination, B-scan, and periodic MRI.
摘要：
■这项工作旨在报告具有挑战性的诊断，治疗,并对1例持续性胎儿血管(PFV)和视网膜母细胞瘤(RB)患者进行随访。
■一个22个月大的男孩，右眼出现单侧RB阶段VB，双眼出现PFV。患者接受了经瞳孔激光消融和全身化疗。
■治疗导致肿瘤完全消退。最后一次全身化疗两年后，磁共振成像（MRI）显示信号强度增加，进行性视神经增强，其中神经内恶性肿瘤不能排除。进行右眼的摘除。组织病理学检查显示，去核球中没有残留活动性恶性肿瘤。
■此病例证明了进行彻底的临床检查以建立正确的诊断并在任何手术前排除RB的重要性。该病例还强调了肿瘤消退后定期随访的重要性，并进行全面的眼科检查。B扫描,定期MRI。
■一个22个月大的男孩，右眼出现单侧RB阶段VB，双眼出现PFV。患者接受了经瞳孔激光消融和全身化疗。
■治疗导致肿瘤完全消退。最后一次全身化疗两年后，磁共振成像（MRI）显示信号强度增加，进行性视神经增强，其中神经内恶性肿瘤不能排除。进行右眼的摘除。组织病理学检查显示，去核球中没有残留活动性恶性肿瘤。
■此病例证明了进行彻底的临床检查以建立正确的诊断并在任何手术前排除RB的重要性。该病例还强调了肿瘤消退后定期随访的重要性，并进行全面的眼科检查。B扫描,定期MRI。
