PDF(Pubmed)
Abstract：
UNASSIGNED: Being an important prognostic predictor in carcinoma oral tongue, neck metastasis poses an adverse impact on prognosis.The management of neck is still controversial. Neck metastasis depends on features like tumor thickness, depth of invasion, lymphovascular invasion and perineural invasion. Thus by correlating these features with the level of nodal metastasis and by correlating clinical and pathological staging, a preoperative assumption for a more conservative neck dissection may be done.
UNASSIGNED: To correlate clinical staging, pathological staging and depth of invasion (DOI) of tumor with cervical nodal metastasis, for a preoperative assumption of a more conservative neck dissection.To study the correlation of additional prognostic features like lymphovascular invasion, perineural invasion, positive resection margin, worst pattern of invasion, lymphocytic infiltration and presence of necrosis with that of cervical nodal metastasis.
UNASSIGNED: The study was conducted on 24 patients of carcinoma oral tongue who underwent resection of the primary with an appropriate neck dissection and their clinical, imaging, and postoperative histopathological findings were correlated.
UNASSIGNED: We found a significant association of the CC (craniocaudal) dimension and radiologically determined DOI (depth of invasion) with the pN also significant association of clinical and radiological DOI with histological DOI. The probability of occult metastasis was found to be more when the MRI-DOI is > 5 mm. The sensitivity and specificity of cN staging were 66.67% and 73.33% respectively. The accuracy of cN was 70.8%.
UNASSIGNED: In the present study a good sensitivity, specificity and accuracy of cN (clinical nodal stage) was found. Craniocaudal (CC) dimension and DOI of the primary tumor measured by MRI is a strong predictor of the disease extension and nodal metastasis. MRI-DOI > 5 mm warrants an elective neck dissection of level I-III. For tumors MRI DOI < 5 mm observation can be recommended with adherence to a strict follow-up.
UNASSIGNED: To correlate clinical staging, pathological staging and depth of invasion (DOI) of tumor with cervical nodal metastasis, for a preoperative assumption of a more conservative neck dissection.To study the correlation of additional prognostic features like lymphovascular invasion, perineural invasion, positive resection margin, worst pattern of invasion, lymphocytic infiltration and presence of necrosis with that of cervical nodal metastasis.
UNASSIGNED: The study was conducted on 24 patients of carcinoma oral tongue who underwent resection of the primary with an appropriate neck dissection and their clinical, imaging, and postoperative histopathological findings were correlated.
UNASSIGNED: We found a significant association of the CC (craniocaudal) dimension and radiologically determined DOI (depth of invasion) with the pN also significant association of clinical and radiological DOI with histological DOI. The probability of occult metastasis was found to be more when the MRI-DOI is > 5 mm. The sensitivity and specificity of cN staging were 66.67% and 73.33% respectively. The accuracy of cN was 70.8%.
UNASSIGNED: In the present study a good sensitivity, specificity and accuracy of cN (clinical nodal stage) was found. Craniocaudal (CC) dimension and DOI of the primary tumor measured by MRI is a strong predictor of the disease extension and nodal metastasis. MRI-DOI > 5 mm warrants an elective neck dissection of level I-III. For tumors MRI DOI < 5 mm observation can be recommended with adherence to a strict follow-up.
摘要：
■是口腔舌癌的重要预后预测因子，颈部转移对预后有不利影响.颈部的管理仍然存在争议。颈部转移取决于肿瘤厚度等特征，入侵深度,淋巴血管浸润和神经周浸润。因此，通过将这些特征与淋巴结转移的水平相关联，并通过将临床和病理分期相关联，术前可以假设更为保守的颈清扫术.
■为了关联临床分期，颈淋巴结转移肿瘤的病理分期和浸润深度（DOI），术前假设更保守的颈部清扫术。为了研究其他预后特征如淋巴管浸润的相关性，神经周浸润,切缘阳性,最糟糕的入侵模式，淋巴细胞浸润和坏死的存在与颈淋巴结转移。
■这项研究是对24例口腔舌癌患者进行的，这些患者接受了适当的颈淋巴结清扫术及其临床，成像,和术后组织病理学结果相关。
■我们发现CC（头尾）尺寸和放射学确定的DOI（侵入深度）与pN之间存在显着关联，临床和放射学DOI与组织学DOI之间也存在显着关联。当MRI-DOI>5mm时，隐匿性转移的可能性更大。cN分期的敏感性和特异性分别为66.67%和73.33%。cN的准确度为70.8%。
■在本研究中，发现cN（临床淋巴结分期）的特异性和准确性。MRI测量的原发性肿瘤的头尾（CC）尺寸和DOI是疾病扩展和淋巴结转移的有力预测指标。MRI-DOI>5mm保证I-III级选择性颈部解剖。对于肿瘤MRI，建议观察DOI<5mm，并遵守严格的随访。
■为了关联临床分期，颈淋巴结转移肿瘤的病理分期和浸润深度（DOI），术前假设更保守的颈部清扫术。为了研究其他预后特征如淋巴管浸润的相关性，神经周浸润,切缘阳性,最糟糕的入侵模式，淋巴细胞浸润和坏死的存在与颈淋巴结转移。
■这项研究是对24例口腔舌癌患者进行的，这些患者接受了适当的颈淋巴结清扫术及其临床，成像,和术后组织病理学结果相关。
■我们发现CC（头尾）尺寸和放射学确定的DOI（侵入深度）与pN之间存在显着关联，临床和放射学DOI与组织学DOI之间也存在显着关联。当MRI-DOI>5mm时，隐匿性转移的可能性更大。cN分期的敏感性和特异性分别为66.67%和73.33%。cN的准确度为70.8%。
■在本研究中，发现cN（临床淋巴结分期）的特异性和准确性。MRI测量的原发性肿瘤的头尾（CC）尺寸和DOI是疾病扩展和淋巴结转移的有力预测指标。MRI-DOI>5mm保证I-III级选择性颈部解剖。对于肿瘤MRI，建议观察DOI<5mm，并遵守严格的随访。
