In this study, Linfen city, one of the most polluted cities in mainland China, was selected as the study site to explore whether air pollutants could affect appendicitis admissions and to identify susceptible populations. Daily data on appendicitis admissions and three principal air pollutants, including inhalable particulate matter (PM10), nitrogen dioxide (NO2), and sulfur dioxide (SO2) were collected in Linfen, China. The impacts of air pollutants on appendicitis were studied by using a generalized additive model (GAM) combined with the quasi-Poisson function. Stratified analyses were also performed by sex, age, and season.
We observed a positive association between air pollution and appendicitis admissions. For a 10 μg/m3 increase in pollutants at lag01, the corresponding relative risks (RRs) and 95% confidence intervals (95% CIs) were 1.0179 (1.0129-1.0230) for PM10, 1.0236 (1.0184-1.0288) for SO2, and 1.0979 (1.0704-1.1262) for NO2. Males and people aged 21-39 years were more susceptible to air pollutants. Regarding seasons, the effects seemed to be stronger during the cold season, but there was no statistically significant difference between the seasonal groups.
Our findings indicated that short-term air pollution exposure was significantly correlated with appendicitis admissions, and active air pollution interventions should be implemented to reduce appendicitis hospitalizations, especially for males and people aged 21-39 years.
■在这项研究中,临汾市,中国大陆污染最严重的城市之一,被选为研究地点,以探讨空气污染物是否会影响阑尾炎入院并确定易感人群。阑尾炎入院和三种主要空气污染物的每日数据,包括可吸入颗粒物(PM10),二氧化氮(NO2),和二氧化硫(SO2)在临汾市收集,中国。通过使用广义加性模型(GAM)结合准泊松函数研究了空气污染物对阑尾炎的影响。还按性别进行了分层分析,年龄,和季节。
■我们观察到空气污染与阑尾炎入院之间存在正相关。对于lag01的污染物增加10μg/m3,PM10的相应相对风险(RRs)和95%置信区间(95%CIs)为1.0179(1.0129-1.0230),SO2为1.0236(1.0184-1.0288),NO2为1.0979(1.0704-1.1262)。男性和21-39岁的人更容易受到空气污染物的影响。关于季节,在寒冷的季节,效果似乎更强,但季节性组间差异无统计学意义。
■我们的研究结果表明,短期空气污染暴露与阑尾炎入院显着相关,应实施积极的空气污染干预措施,以减少阑尾炎的住院治疗,尤其是男性和21-39岁的人。