Abstract：
The objectives of this narrative review are to update readers on the current state-of-the-art regarding diverse approaches for the treatment of pain, global symptoms, or adequate relief in irritable bowel syndrome (IBS). The article appraises medications, dietary interventions including low fermentable oligosaccharides, disaccharides, and monosaccharides and polyols (FODMAP) diet, fecal microbial transplantation (FMT), electrical approaches, and behavioral therapies including cognitive behavioral therapy (CBT), gut-directed hypnotherapy (GDH), mindfulness, and open-label placebo. Current evidence demonstrates only modest benefit in global IBS symptoms and pain relief. A future approach that identifies pathophysiological mechanisms of IBS through validated biomarkers has the potential to individualize treatment of patients rather than sequential therapeutic trial and error approaches.
摘要：
这篇叙述性综述的目的是让读者了解目前关于疼痛治疗的各种方法的最新情况，全球症状，或肠易激综合征（IBS）的充分缓解。这篇文章评价了药物，饮食干预，包括低可发酵寡糖，二糖，和单糖和多元醇（FODMAP）饮食，粪便微生物移植（FMT），电气方法，和行为疗法，包括认知行为疗法（CBT），肠道定向催眠疗法（GDH），正念,和开放标签安慰剂。目前的证据表明，在全球IBS症状和疼痛缓解方面仅有适度的益处。通过验证的生物标志物鉴定IBS病理生理机制的未来方法具有使患者个体化治疗而不是序贯治疗试验和错误方法的潜力。
