关键词: Abnormal hair growth case report hypertrichosis knee arthroplasty postsurgical wound healing

来  源:   DOI:10.4103/ijd.ijd_661_21   PDF(Pubmed)

Abstract:
Hypertrichosis is a condition characterized by the presence of an abnormal increase in the number of hairs and either occurs in a localized pattern or a generalized pattern. Localized hypertrichosis around a healing wound is an infrequent postsurgical complication. A 60-year-old Asian man came for a consultation because of an increase in the amount of hair around his 2-month postsurgical wound of right knee arthroplasty. Neither history of topical medications nor systemic medications, which can cause hypertrichosis, were presented. A diagnosis of postsurgical hypertrichosis was made clinically without any laboratory investigations. The patient was reassured that the medication was not necessary and he was appointed for follow-ups. Within the next 4 months, the hypertrichosis resolved spontaneously without any treatment. The case demonstrates the correlation between wound healing and hair morphogenesis, especially as both processes involve some similar growth factors and signaling molecules. Further studies might lead to discovery and better management of hair disorders.
摘要:
多毛症是一种以毛发数量异常增加为特征的病症,并且以局部模式或广义模式发生。愈合伤口周围的局部多毛症是罕见的术后并发症。一名60岁的亚洲男子前来咨询,因为他的右膝关节置换术后2个月伤口周围的毛发数量增加。既没有局部用药史,也没有全身用药史,会导致多毛症,被介绍了。在没有任何实验室检查的情况下,临床诊断为术后多毛症。患者被保证不需要药物治疗,并被任命进行随访。在接下来的4个月里,多毛症无需任何治疗即可自行缓解。该病例证明了伤口愈合与毛发形态发生之间的相关性,特别是这两个过程都涉及一些相似的生长因子和信号分子。进一步的研究可能会导致发现和更好地管理头发疾病。
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