Abstract：
UNASSIGNED: Paraganglioma (PG); also known as Glomus Tumor, is a rare neoplastic entity that originates from neural crest cells. It can manifest in different patterns, chiefly benign but others are locally invasive and malignant in behavior. Due to the prevalence of other more common types of neck masses and Paraganglioma\'s exceeding rarity, misdiagnoses can easily take place, and this results in higher patient morbidity and mortality rates. Preoperative diagnosis constitutes a major clinical challenge, especially in patients with a previous surgical history in the neck region like our patient.
METHODS: We are hereby presenting the case of a 56-year-old female with a known history of total thyroidectomy, who presented to our department with a progressively growing painful recurring neck mass two years following her total thyroidectomy. The preoperative diagnostic assessment revealed two unilateral synchronous masses encapsulating the Right Common Carotid Artery and occupying the common carotid bifurcation.
UNASSIGNED: Complete surgical resection of the lesions after isolation from the surrounding anatomical structures was done. Subsequent histopathological and immunohistochemical analyses of the specimens established the diagnosis of a Carotid Body Tumor (CBT).
CONCLUSIONS: CBTs are rare vascular neoplasia, and they possess the potential for malignant transformation. This neoplasia warrants investigation and documentation to establish innovative diagnostic parameters and accomplish timely surgical interventions. To the best of our knowledge, this is the first documented case of a unilateral synchronous malignant Carotid Body Tumor from Syria. Surgery remains the treatment of choice, while radio-/chemotherapy is reserved for non-surgical cases only.
METHODS: We are hereby presenting the case of a 56-year-old female with a known history of total thyroidectomy, who presented to our department with a progressively growing painful recurring neck mass two years following her total thyroidectomy. The preoperative diagnostic assessment revealed two unilateral synchronous masses encapsulating the Right Common Carotid Artery and occupying the common carotid bifurcation.
UNASSIGNED: Complete surgical resection of the lesions after isolation from the surrounding anatomical structures was done. Subsequent histopathological and immunohistochemical analyses of the specimens established the diagnosis of a Carotid Body Tumor (CBT).
CONCLUSIONS: CBTs are rare vascular neoplasia, and they possess the potential for malignant transformation. This neoplasia warrants investigation and documentation to establish innovative diagnostic parameters and accomplish timely surgical interventions. To the best of our knowledge, this is the first documented case of a unilateral synchronous malignant Carotid Body Tumor from Syria. Surgery remains the treatment of choice, while radio-/chemotherapy is reserved for non-surgical cases only.
摘要：
■副神经节瘤（PG）；也称为血管球瘤，是一种罕见的肿瘤实体，起源于神经c细胞。它可以表现为不同的模式，主要是良性的，但其他行为是局部侵入性和恶性的。由于其他更常见类型的颈部肿块和副神经节瘤的罕见性，误诊很容易发生，这导致更高的患者发病率和死亡率。术前诊断构成了主要的临床挑战，尤其是像我们的病人一样，在颈部有手术史的病人。
方法：我们特此介绍一名56岁女性，已知有甲状腺全切除术史，她在甲状腺全切除术后两年出现了逐渐增加的疼痛性复发性颈部肿块。术前诊断评估显示，两个单侧同步肿块包裹了右颈总动脉并占据了颈总分叉。
■在与周围解剖结构隔离后，对病灶进行完整的手术切除。随后标本的组织病理学和免疫组织化学分析确定了颈动脉体瘤（CBT）的诊断。
结论：CBTs是罕见的血管瘤，它们具有恶性转化的潜力。这种肿瘤需要进行调查和记录，以建立创新的诊断参数并及时进行手术干预。据我们所知,这是叙利亚首例单侧同步恶性颈动脉体瘤病例.手术仍然是首选的治疗方法，而放疗/化疗仅适用于非手术病例。
方法：我们特此介绍一名56岁女性，已知有甲状腺全切除术史，她在甲状腺全切除术后两年出现了逐渐增加的疼痛性复发性颈部肿块。术前诊断评估显示，两个单侧同步肿块包裹了右颈总动脉并占据了颈总分叉。
■在与周围解剖结构隔离后，对病灶进行完整的手术切除。随后标本的组织病理学和免疫组织化学分析确定了颈动脉体瘤（CBT）的诊断。
结论：CBTs是罕见的血管瘤，它们具有恶性转化的潜力。这种肿瘤需要进行调查和记录，以建立创新的诊断参数并及时进行手术干预。据我们所知,这是叙利亚首例单侧同步恶性颈动脉体瘤病例.手术仍然是首选的治疗方法，而放疗/化疗仅适用于非手术病例。
