PDF(Pubmed)
Abstract：
In the past, BCOR-CCNB3 sarcoma was believed to be comparable to Ewing\'s sarcoma; however, current research has proven that it is, in reality, a distinct type of the illness, now classified as a distinct entity under undifferentiated round cell sarcomas. This tumour most frequently affects teenagers and young adults, and it is more prevalent in men. It can form in both bone and soft tissue, and it appears most frequently in the pelvis, lower extremities, and paraspinal region. Here, we describe a case of a soft tissue tumour in the proximal posterior portion of the right thigh of a 12-year-old male that was subsequently shown to be a BCOR-CCNB3 fusion using genetic analysis.
摘要：
在过去,BCOR-CCNB3肉瘤被认为与尤文肉瘤相当；然而，目前的研究已经证明，在现实中,一种独特的疾病，现在被归类为未分化圆形细胞肉瘤的独特实体。这种肿瘤最常影响青少年和年轻人，它在男性中更为普遍。它可以在骨骼和软组织中形成，它最常见于骨盆，下肢,和椎旁区域。这里,我们描述了一例12岁男性右大腿近端后部的软组织肿瘤，随后通过遗传分析显示为BCOR-CCNB3融合。
