Abstract：
The macula, as the central part of the retina, plays an important role in the reading process. However, its morphology has not been previously studied in the context of dyslexia. In this research, we compared the thickness of the fovea, parafovea and perifovea between dyslexic subjects and normal controls, in 11 retinal segmentations obtained by optical coherence tomography (OCT). With this aim, we considered the nine sectors of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid and also summarized data from sectors into inner ring subfield (parafovea) and outer ring subfield (perifovea). The thickness in all the four parafoveal sectors was significantly thicker in the complete retina, inner retina and middle retina of both eyes in the dyslexic group, as well as other macular sectors (fovea and perifovea) in the inner nuclear layer (INL), inner plexiform layer (IPL), IPL + INL and outer plexiform layer + outer nuclear layer (OPL + ONL). Additionally, the inner ring subfield (parafovea), but not the outer ring subfield (perifovea), was thicker in the complete retina, inner retina, middle retina (INL + OPL + ONL), OPL + ONL, IPL + INL and INL in the dyslexic group for both eyes. In contrast, no differences were found between the groups in any of the sectors or subfields of the outer retina, retinal nerve fiber layer, ganglion cell layer or ganglion cell complex in any eye. Thus, we conclude from this exploratory research that the macular morphology differs between dyslexic and normal control subjects, as measured by OCT, especially in the parafovea at middle retinal segmentations.
摘要：
黄斑,作为视网膜的中心部分，在阅读过程中起着重要的作用。然而,以前没有在阅读障碍的背景下研究其形态。在这项研究中,我们比较了中央凹的厚度，诵读困难受试者和正常对照之间的半腹和半腹，在光学相干断层扫描（OCT）获得的11个视网膜分割。为了这个目标,我们考虑了糖尿病视网膜病变早期治疗研究（ETDRS）网格的9个部门，并将部门的数据汇总到内环子场（旁瓣）和外环子场（旁瓣）。在完整的视网膜中，所有四个旁凹区域的厚度都明显较厚，阅读障碍组双眼的内部视网膜和中间视网膜，以及内核层（INL）中的其他黄斑区（中央凹和中央凹），内丛状层（IPL），IPL+INL和外丛状层+外核层(OPL+ONL)。此外,内环子场(parafovea)，但不是外环子场(半凹)，整个视网膜较厚，内部视网膜,视网膜中部（INL+OPL+ONL），OPL+ONL,双眼阅读困难组的IPL+INL和INL。相比之下,在外视网膜的任何部分或子场的组间没有发现差异，视网膜神经纤维层，神经节细胞层或神经节细胞复合体在任何眼睛。因此，我们从这项探索性研究中得出结论，阅读困难和正常对照受试者的黄斑形态不同，根据OCT的测量，尤其是在中间视网膜节段的旁瓣中。
