Abstract：
As the global coronavirus disease 2019 (COVID-19) pandemic continues to sweep across the globe, reports of kidney involvement in adult patients infected with COVID-19 have been documented, and recently, cases in the pediatric population have also been reported. This report highlights the case of an 11-year-old boy who developed acute kidney injury presenting as gross hematuria, proteinuria, and hypertension immediately after a COVID-19 infection. A renal biopsy allowed us to diagnose the patient with post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis. Oral prednisolone and cyclophosphamide treatments were initiated after methylprednisolone pulse therapy administration. Currently, the patient is receiving medical treatment for five weeks, and his renal function is gradually recovering. Previous studies have suggested that, although quite rare, a variety of kidney complications can occur after COVID-19 infection or vaccination, and it is recommended to monitor renal function through evaluation. Herein, we report a pediatric case of post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis consistent with rapidly progressive glomerulonephritis.
摘要：
随着2019年全球冠状病毒病(COVID-19)大流行继续席卷全球，已记录了感染COVID-19的成年患者肾脏受累的报告，最近,在儿科人群中的病例也有报道.本报告重点介绍了一例11岁男孩的急性肾损伤，表现为肉眼血尿，蛋白尿,COVID-19感染后立即出现高血压。肾活检使我们能够诊断出患有COVID-19后感染相关的新月体免疫介导的肾小球肾炎的患者。甲基强的松龙冲击治疗后开始口服泼尼松龙和环磷酰胺治疗。目前,病人正在接受治疗五周，肾功能逐渐恢复.以前的研究表明，虽然相当罕见，COVID-19感染或接种疫苗后可发生多种肾脏并发症，建议通过评估监测肾功能。在这里，我们报告了1例COVID-19后感染相关的新生新月体免疫介导的肾小球肾炎与快速进展性肾小球肾炎一致的儿科病例.
