PDF(Pubmed)
Abstract：
Amyloidosis is often caused by the abnormal extracellular accumulation of amyloid in organs and tissues. This condition, affecting the head and neck region, is typically localized, and may also involve the oral cavity, particularly the tongue and buccal mucosa. As a solitary manifestation, the localized amyloidosis occurring intraosseous is highly infrequent. In addition, localized amyloidosis has a great rate of recurrence. In this paper, a 50-year-old female patient with the chief complaint of pain in the anterior of the maxilla is reported. According to clinical examination, no significant pathologic lesion was seen. The radiographic image showed a radiolucent lesion around teeth four and five. The treatment of choice for the patient was an excisional biopsy. As amyloidosis diagnosis is clinically challenging, biopsy and histologic examination of lesions are necessary in this regard. Accordingly, it is concluded that long-term follow-up is mandatory in case of localized amyloidosis because late recurrence can occur in some cases.
摘要：
淀粉样变性通常是由器官和组织中淀粉样蛋白的异常细胞外积累引起的。这个条件,影响头部和颈部，通常是本地化的，也可能涉及口腔，尤其是舌头和颊粘膜。作为一种孤独的表现，骨内发生的局部淀粉样变性很少见。此外,局限性淀粉样变性复发率高。在本文中,据报道,1例50岁女性患者主诉为上颌骨前部疼痛.根据临床检查,未见明显的病理性病变。射线照相图像显示四号和五号牙齿周围有射线可透的病变。患者的治疗选择是切除活检。由于淀粉样变性的诊断在临床上具有挑战性，在这方面，活检和病变的组织学检查是必要的。因此，结论是，在局部淀粉样变性的情况下，长期随访是强制性的，因为在某些情况下可能会发生晚期复发。
