Abstract：
Biosensors that sense the concentration of a specified target and produce a specific signal output have become important technology for biological analysis. Recently, intelligent biosensors have received great interest due to their adaptability to meet sophisticated demands. Advances in developing standard modules and carriers in synthetic biology have shed light on intelligent biosensors that can implement advanced analytical processing to better accommodate practical applications. This review focuses on intelligent synthetic biology-enabled biosensors (SBBs). First, we illustrate recent progress in intelligent SBBs with the capability of computation, memory storage, and self-calibration. Then, we discuss emerging applications of SBBs in point-of-care testing (POCT) and wearable monitoring. Finally, future perspectives on intelligent SBBs are proposed.
摘要：
感测特定目标的浓度并产生特定信号输出的生物传感器已成为生物分析的重要技术。最近,智能生物传感器由于其满足复杂需求的适应性而受到了极大的关注。在合成生物学中开发标准模块和载体的进展已经揭示了智能生物传感器，这些传感器可以实现先进的分析处理以更好地适应实际应用。这篇综述的重点是智能合成生物学启用的生物传感器(SBB)。首先,我们说明了具有计算能力的智能SBB的最新进展，内存存储，和自校准。然后，我们讨论了SBB在即时检测（POCT）和可穿戴监测中的新兴应用。最后,提出了智能SBB的未来观点。
