Abstract：
BACKGROUND: Synchronous visceral malignancy is rare especially for esophagogastric junction adenocarcinoma combined with malignancy in the pancreas. So far only 7 cases of combined partial pancreatoduodenectomy and esophagectomy for synchronous malignancy have been described in the literature and none for combined total pancreatectomy and esophagectomy.
METHODS: We report the case of a 67-year-old male patient, who underwent multi-modality treatment including two-stage total pancreatoduodenectomy and subsequent Ivor-Lewis esophagectomy for synchronous adenocarcinoma of the distal esophagus and pancreatic multilocal metastases of a renal cell carcinoma after nephrectomy 17 years ago. Pathology revealed R0 resections for both malignancies and there were no postoperative complications. A 12 months follow-up showed no signs of recurrence and a good quality of life.
CONCLUSIONS: Curative-intent, combined oncological two-stage open total pancreatoduodenectomy and esophagectomy with several days interval is safe and feasible in selected cases when performed by an experienced interdisciplinary team in a high-volume surgical center.
METHODS: We report the case of a 67-year-old male patient, who underwent multi-modality treatment including two-stage total pancreatoduodenectomy and subsequent Ivor-Lewis esophagectomy for synchronous adenocarcinoma of the distal esophagus and pancreatic multilocal metastases of a renal cell carcinoma after nephrectomy 17 years ago. Pathology revealed R0 resections for both malignancies and there were no postoperative complications. A 12 months follow-up showed no signs of recurrence and a good quality of life.
CONCLUSIONS: Curative-intent, combined oncological two-stage open total pancreatoduodenectomy and esophagectomy with several days interval is safe and feasible in selected cases when performed by an experienced interdisciplinary team in a high-volume surgical center.
摘要：
背景：同步内脏恶性肿瘤很少见，尤其是食管胃结合部腺癌合并胰腺恶性肿瘤。到目前为止，文献中仅描述了7例联合胰十二指肠部分切除术和食管切除术治疗同步恶性肿瘤，而没有一例联合全胰腺切除术和食管切除术。
方法：我们报告一例67岁男性患者，17年前接受了多模态治疗，包括两阶段全胰十二指肠切除术和随后的Ivor-Lewis食管切除术，用于治疗食管远端同步腺癌和肾细胞癌的胰腺多局部转移。病理显示R0切除两种恶性肿瘤，无术后并发症。12个月的随访显示没有复发的迹象和良好的生活质量。
结论：治疗意图，在选定的病例中,由高容量外科中心的经验丰富的跨学科团队进行的肿瘤两阶段开放式全胰十二指肠切除术和食管切除术联合治疗是安全可行的.
方法：我们报告一例67岁男性患者，17年前接受了多模态治疗，包括两阶段全胰十二指肠切除术和随后的Ivor-Lewis食管切除术，用于治疗食管远端同步腺癌和肾细胞癌的胰腺多局部转移。病理显示R0切除两种恶性肿瘤，无术后并发症。12个月的随访显示没有复发的迹象和良好的生活质量。
结论：治疗意图，在选定的病例中,由高容量外科中心的经验丰富的跨学科团队进行的肿瘤两阶段开放式全胰十二指肠切除术和食管切除术联合治疗是安全可行的.
