Abstract：
Hypokalemic periodic paralysis (HPP) is a rare channelopathy characterized by episodic attacks of acute muscle weakness concomitant with hypokalemia. The etiology of hypokalemia is the shift of potassium into the cells, and the clinical symptoms resolve when potassium starts to leak back to the serum. Most of the time, the underlying ion channel defects are well compensated, and an additional trigger is often required to initiate an attack. Well-known trigger factors include carbohydrate-rich meals, exercise followed by rest, stress, cold weather, and alcohol consumption.
Here, we present the case of a 26-year-old Asian man who suffered from an acute onset of bilateral lower limb weakness with hypokalemia following dexamethasone injection. He was diagnosed with HPP.
We would like to remind physicians to think of steroids as an unusual precipitating factor while managing patients with HPP, per results of this case study.
Here, we present the case of a 26-year-old Asian man who suffered from an acute onset of bilateral lower limb weakness with hypokalemia following dexamethasone injection. He was diagnosed with HPP.
We would like to remind physicians to think of steroids as an unusual precipitating factor while managing patients with HPP, per results of this case study.
摘要：
背景：低钾性周期性麻痹（HPP）是一种罕见的通道病，其特征是急性肌无力发作并伴有低钾血症。低钾血症的病因是钾转移到细胞中，当钾开始泄漏回血清时，临床症状就会消失。大多数时候,潜在的离子通道缺陷得到了很好的补偿，并且通常需要额外的触发器来发起攻击。众所周知的触发因素包括富含碳水化合物的膳食，运动后休息，压力，寒冷的天气,和酒精消费。
方法：这里，我们介绍了1例26岁的亚裔男子,他在注射地塞米松后出现急性双侧下肢无力并低钾血症.他被诊断为HPP。
结论：我们想提醒医生在治疗HPP患者时，将类固醇视为一种不寻常的促发因素，根据本案例研究的结果。
方法：这里，我们介绍了1例26岁的亚裔男子,他在注射地塞米松后出现急性双侧下肢无力并低钾血症.他被诊断为HPP。
结论：我们想提醒医生在治疗HPP患者时，将类固醇视为一种不寻常的促发因素，根据本案例研究的结果。
