PDF(Pubmed)
Abstract：
UNASSIGNED: Living kidney donors (LKDs) experience perioperative anxiety. We designed the following study to evaluate the anxiolytic effect of transcutaneous electrical acupoint stimulation (TEAS) during the perioperative period in a group of LKDs undergoing laparotomy nephrectomy.
UNASSIGNED: LKDs were randomly assigned to either the TEAS or control group. Participants in the TEAS group received 30min of intervention (6-15 mA, 2-100 Hz), at Yintang (EX-HN-3), bilateral Taichong (LR3) and Neiguan (PC6) one day before surgery (D0), before induction of anesthesia (D1) and one day after surgery (D2). The participants in the control group received the same placement of electrodes but without electrical stimulation. Venous blood was collected before each intervention. Anxiety levels and recovery profiles were recorded.
UNASSIGNED: LKDs in the TEAS group had lower anxiety level than those in the control group at D1, D2 and three days after surgery (D3). The percentage differences were: 33.3%, 25.0%, and 22.2%; [95% confidence interval (CI), (-55.1%, -11.6%), (-47.4%, -2.6%), and (-42.3%, -2.2%); P = 0.005, P = 0.034, and P = 0.035; respectively]. LKDs who received TEAS had better sleep quality and short-term recovery profiles than those in the control group. The plasma levels of 5-hydroxytryptamine (5-HT) and melatonin (MT) in the TEAS group were significantly higher than those in the control group at D1 and D2 (5-HT: P = 0.001, and P < 0.001; MT: P = 0.006, and P = 0.001). At the 3-month follow up, fewer LKDs in the TEAS group had incisional pain when compared to the control group (P = 0.032).
UNASSIGNED: Perioperative TEAS decreased perioperative anxiety and facilitated postoperative recovery in the LKDs, and potential decreased the development of chronic pain. Trial Registration: Registered at ChiCTR2000029891, http://www.chictr.org.cn/listbycreater.aspx.
UNASSIGNED: LKDs were randomly assigned to either the TEAS or control group. Participants in the TEAS group received 30min of intervention (6-15 mA, 2-100 Hz), at Yintang (EX-HN-3), bilateral Taichong (LR3) and Neiguan (PC6) one day before surgery (D0), before induction of anesthesia (D1) and one day after surgery (D2). The participants in the control group received the same placement of electrodes but without electrical stimulation. Venous blood was collected before each intervention. Anxiety levels and recovery profiles were recorded.
UNASSIGNED: LKDs in the TEAS group had lower anxiety level than those in the control group at D1, D2 and three days after surgery (D3). The percentage differences were: 33.3%, 25.0%, and 22.2%; [95% confidence interval (CI), (-55.1%, -11.6%), (-47.4%, -2.6%), and (-42.3%, -2.2%); P = 0.005, P = 0.034, and P = 0.035; respectively]. LKDs who received TEAS had better sleep quality and short-term recovery profiles than those in the control group. The plasma levels of 5-hydroxytryptamine (5-HT) and melatonin (MT) in the TEAS group were significantly higher than those in the control group at D1 and D2 (5-HT: P = 0.001, and P < 0.001; MT: P = 0.006, and P = 0.001). At the 3-month follow up, fewer LKDs in the TEAS group had incisional pain when compared to the control group (P = 0.032).
UNASSIGNED: Perioperative TEAS decreased perioperative anxiety and facilitated postoperative recovery in the LKDs, and potential decreased the development of chronic pain. Trial Registration: Registered at ChiCTR2000029891, http://www.chictr.org.cn/listbycreater.aspx.
摘要：
■活体肾脏捐献者（LKD）经历围手术期焦虑。我们设计了以下研究，以评估经皮穴位电刺激（TEAS）在一组接受开腹肾切除术的LKD围手术期的抗焦虑作用。
■LKD被随机分配到TEAS或对照组。TEAS组的参与者接受30分钟的干预（6-15mA，2-100Hz),在印堂(EX-HN-3)，术前1天（D0）双侧太冲（LR3）和内关（PC6），麻醉诱导前（D1）和手术后一天（D2）。对照组的参与者接受了相同的电极放置，但没有电刺激。每次干预前采集静脉血。记录焦虑水平和恢复情况。
■TEAS组的LKD在D1，D2和术后3天（D3）的焦虑水平低于对照组。百分比差异为：33.3％，25.0%,和22.2%；[95%置信区间(CI)，（-55.1%，-11.6%），（-47.4%，-2.6%），和(-42.3%，-2.2％）；分别为P=0.005，P=0.034和P=0.035]。与对照组相比，接受TEAS的LKD具有更好的睡眠质量和短期恢复状况。TEAS组血浆5-羟色胺(5-HT)和褪黑素(MT)水平在D1和D2时均明显高于对照组(5-HT:P=0.001,P<0.001;MT:P=0.006,P=0.001)。在3个月的随访中，与对照组相比,TEAS组出现切口疼痛的LKD较少(P=0.032).
■围手术期TEAS降低了LKD患者的围手术期焦虑，促进了术后恢复，和潜在的减少慢性疼痛的发展。试用注册：在ChiCTR2000029891注册，http://www。chictr.org.cn/listbycreater。aspx.
■LKD被随机分配到TEAS或对照组。TEAS组的参与者接受30分钟的干预（6-15mA，2-100Hz),在印堂(EX-HN-3)，术前1天（D0）双侧太冲（LR3）和内关（PC6），麻醉诱导前（D1）和手术后一天（D2）。对照组的参与者接受了相同的电极放置，但没有电刺激。每次干预前采集静脉血。记录焦虑水平和恢复情况。
■TEAS组的LKD在D1，D2和术后3天（D3）的焦虑水平低于对照组。百分比差异为：33.3％，25.0%,和22.2%；[95%置信区间(CI)，（-55.1%，-11.6%），（-47.4%，-2.6%），和(-42.3%，-2.2％）；分别为P=0.005，P=0.034和P=0.035]。与对照组相比，接受TEAS的LKD具有更好的睡眠质量和短期恢复状况。TEAS组血浆5-羟色胺(5-HT)和褪黑素(MT)水平在D1和D2时均明显高于对照组(5-HT:P=0.001,P<0.001;MT:P=0.006,P=0.001)。在3个月的随访中，与对照组相比,TEAS组出现切口疼痛的LKD较少(P=0.032).
■围手术期TEAS降低了LKD患者的围手术期焦虑，促进了术后恢复，和潜在的减少慢性疼痛的发展。试用注册：在ChiCTR2000029891注册，http://www。chictr.org.cn/listbycreater。aspx.
