探索革兰氏阳性细菌中肽 - 膜相互作用的计算工具。
关键词: 3-HBA, 3–Hydroxybenzoic Acid AAC, Amino Acid Composition ABC, ATP-binding cassette ACD, Available Chemicals Database AIP, Autoinducing Peptide AMP, Anti-Microbial Peptide ATP, Adenosine Triphosphate Agr, Accessory gene regulator BFE, Binding Free Energy BIP Inhibitors BIP, Biofilm Inhibitory Peptides BLAST, Basic Local Alignment Search Tool BNB, Bernoulli Naïve-Bayes CADD, Computer-Aided Drug Design CSP, Competence Stimulating Peptide CTD, Composition-Transition-Distribution D, Aspartate DCH, 3,3′-(3,4-dichlorobenzylidene)-bis-(4-hydroxycoumarin) DT, Decision Tree FDA, Food and Drug Administration GBM, Gradient Boosting Machine GDC, g-gap Dipeptide GNB, Gaussian NB Gram-positive bacteria H, Histidine H-Kinase, Histidine Kinase H-phosphotransferase, Histidine Phosphotransferase HAM, Hamamelitannin HGM, Human Gut Microbiota HNP, Human Neutrophil Peptide IT, Information Theory Features In silico approaches KNN, K-Nearest Neighbors MCC, Mathew Co-relation Coefficient MD, Molecular Dynamics MDR, Multiple Drug Resistance ML, Machine Learning MRSA, Methicillin Resistant S. aureus MSL, Multiple Sequence Alignment OMR, Omargliptin OVP, Overlapping Property Features PCP, Physicochemical Properties PDB, Protein Data Bank PPIs, Protein-Protein Interactions PSM, Phenol-Soluble Modulin PTM, Post Translational Modification QS, Quorum Sensing QSCN, QS communication network QSHGM, Quorum Sensing of Human Gut Microbes QSI, QS Inhibitors QSIM, QS Interference Molecules QSP inhibitors QSP predictors QSP, QS Peptides QSPR, Quantitative Structure Property Relationship Quorum sensing peptides RAP, RNAIII-activating protein RF, Random Forest RIP, RNAIII-inhibiting peptide ROC, Receiver Operating Characteristic SAR, Structure-Activity Relationship SFS, Sequential Forward Search SIT, Sitagliptin SVM, Support Vector Machine TCS, Two-Component Sensory TRAP, Target of RAP TRG, Trelagliptin WHO, World Health Organization mRMR, minimum Redundancy and Maximum Relevance
来 源:
DOI:10.1016/j.csbj.2023.02.051
PDF(Pubmed)