关键词: case report immunohistochemistry myoid gonadal stromal spindle cell tumors testis

Mesh : Humans Male Adult Testicular Neoplasms / diagnosis surgery metabolism Sex Cord-Gonadal Stromal Tumors / diagnosis surgery pathology Orchiectomy Immunohistochemistry

来  源:   DOI:10.1177/10668969231160256

Abstract:
The myoid gonadal stromal tumor is a very rare testicular spindle cell tumor. Few cases have been reported in the literature from 1977 to 2022. It was an emerging entity in the fourth edition of the WHO Classification of Tumors of the Urinary System and Male Genital Organs and has been instated as a full benign entity in the new edition of 2022. We report herein an additional case of a myoid gonadal stromal tumor. It was a 27-year-old man who presented with an asymptomatic mass in his left testicle for 2 months. The mass was confirmed by ultrasound as a 3 cm solid well-circumscribed lesion for which orchiectomy has been performed. The histological analysis of the specimen and the immunohistochemistry staining was consistent with a myoid gonadal stromal tumor. The characteristics of this tumor are summarized in well-circumscribed, nonencapsulated masses of uniform spindle cells, and immunohistochemically, tumor cells coexpress SMA and S-100 protein. The benign behavior of this tumor is demonstrated by our results and those presented in the previous cases reported in the literature.
摘要:
肌样性腺间质瘤是一种非常罕见的睾丸梭形细胞瘤。从1977年到2022年,文献中很少报道病例。它是世卫组织《泌尿系统和男性生殖器官肿瘤分类》第四版的新兴实体,并在2022年新版中被列为完整的良性实体。我们在此报告另一例肌样性腺间质瘤。这是一名27岁的男子,他的左睾丸出现无症状的肿块2个月。通过超声确认肿块为3厘米的实心病灶,已进行了睾丸切除术。标本的组织学分析和免疫组织化学染色与肌样性腺间质瘤一致。总结了这种肿瘤的特点,非包囊的均匀梭形细胞,和免疫组织化学,肿瘤细胞共表达SMA和S-100蛋白。我们的结果和文献中报道的先前病例中提出的结果证明了该肿瘤的良性行为。
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