PDF(Pubmed)
Abstract：
Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood, presenting with purpura, predominantly of the lower extremities and occasionally with renal involvement as well. Although associated with childhood, HSP, although rarely, can also develop in adults as well. Here we present a patient in his sixties, presenting with a myriad of rash units on his lower extremities, including bullous ones, and a constellation of chronic kidney failure. Skin and renal biopsy specimens revealed morphological changes and immune depositions representative of HSP. Despite treatment, the patient\'s kidney failure slowly progressed, and he expired eight months after his presentation due to associated complications. Although rare, the bullous form of HSP can be viewed as a more aggressive form of the disease, as seen by the presentation constellation and rapid progression in our case.
摘要：
过敏性紫癜（HSP）是儿童期最常见的血管炎，出现紫癜，主要是下肢，偶尔也有肾脏受累。虽然与童年有关，HSP,虽然很少,也可以在成人中发展。这里我们介绍一个60多岁的病人，他的下肢出现了无数的皮疹，包括bullous的，和一系列慢性肾衰竭。皮肤和肾活检标本显示HSP的形态学变化和免疫沉积。尽管治疗,病人的肾衰竭进展缓慢，由于相关的并发症，他在演讲后八个月就过期了。虽然罕见，HSP的大疱性形式可以被视为一种更具侵袭性的疾病形式，正如我们案例中的呈现星座和快速发展所看到的那样。
