关键词: Acute repetitive seizures Antiseizure medications Diazepam Midazolam Seizure clusters

Mesh : Child Adult Humans Benzodiazepines / therapeutic use Anticonvulsants / therapeutic use pharmacology Seizures / drug therapy Status Epilepticus / drug therapy Administration, Intranasal

来  源:   DOI:10.1007/s13311-023-01359-3   PDF(Pubmed)

Abstract:
Acute seizure therapies given out of the hospital are important for interrupting acute repetitive and prolonged seizures and preventing hospitalization. These vary in their administration routes, indications for children and adults, pharmacologic profiles, and efficacy. We reviewed and compared the uses of current formulations available to treat acute seizures, including newly released intranasal (IN) benzodiazepines and older formulations which are widely used for interrupting seizures.
摘要:
在医院外给予急性癫痫发作治疗对于中断急性重复性和长期癫痫发作以及防止住院很重要。这些在管理途径上各不相同,儿童和成人的适应症,药理学简介,和功效。我们回顾并比较了目前可用于治疗急性癫痫发作的制剂的用途,包括新发布的鼻内(IN)苯二氮卓类药物和较旧的制剂,广泛用于中断癫痫发作。
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