123-Iodine MIBG in the Assessment of Sympathetic Denervation in Ogilvie's Syndrome.

123 - 碘 MIBG 在评估 Ogilvie 综合征交感神经支配中的应用。

• 发表时间: Mar 2023
• 来源期刊: World J Nucl Med
• DOI: 10.1055/s-0042-1750387
• PMID: 36923981
• 文章类型: Case Reports
• 作者列表: Bhoil A,Vinjamuri S

关键词: I-123 MIBG; Ogilvie's syndrome; autonomic neuropathy; pseudo-obstruction; sympathetic dysfunction

Abstract

123-Iodine metaiodobenzylguanidine (I-123 MIBG) imaging is frequently used in the assessment of sympathetic innervation and autonomic dysfunction in patients with cardiac failure, neurodegenerative Parkinson\'s syndrome, multiple system atrophy, myotonic dystrophy, and diabetic mellitus. The etiology of pseudo-obstruction remains unknown with likely imbalance between sympathetic and parasympathetic innervation proposed as a hypothesis. We present a case demonstrating the utility of I-123 MIBG scintigraphy for evaluating a case of pseudo-obstruction requiring frequent hospitalization due to progressive complex autoimmune neurological disorder.

摘要

123-碘偏碘苄基胍（I-123MIBG）成像经常用于评估心力衰竭患者的交感神经支配和自主神经功能障碍，神经退行性帕金森综合征，多系统萎缩,强直性肌营养不良,和糖尿病。假性梗阻的病因尚不清楚，作为假设提出的交感神经和副交感神经支配之间可能存在失衡。我们提出了一个案例，证明了I-123MIBG闪烁显像术可用于评估由于进行性复杂的自身免疫性神经系统疾病而需要频繁住院的假性梗阻病例。