关键词: Polyvinyl alcohol particles tris-acryl gelatin microspheres uterine artery embolization uterine fibroid

来  源:   DOI:10.4274/tjod.galenos.2023.43778

Abstract:
UNASSIGNED: To identify the preferred agent by comparing the therapeutic efficacy, degree of infarction, and side effects of polyvinyl alcohol particles (PVA) and tris-acryl gelatin embolization (TAGM) agents in uterine artery embolization.
UNASSIGNED: We included available articles comparing PVA with TAGM embolization agents in the management of fibroids. The primary outcomes included the decrease in uterine volume (%), decrease in dominant tumor volume (%), fibroid infarction rate, complete infarction fibroid, complications, pain score after 24 h, procedure time (minutes), duration of hospital stay, fluoroscopy time (minutes), and the change in symptom severity score.
UNASSIGNED: Eight articles that met our inclusion criteria were included in this study. Our analysis yielded an overall superiority of PVA compared to TAGM regarding complete fibroid infarction rate at the first 24 h. However, TAGM was better than PVA concerning <90% infarction rate outcome. While both embolization techniques showed similar effects regarding the change in symptom severity score, the percentage of decrease in uterine volume, percentage of decrease of dominant tumor volume, 90-99% infarction rate, complete infarction rate when assessed after the first 24 h, pain score after the first 24 h, procedure time, fluoroscopy time, minor, and major complications.
UNASSIGNED: Both PVA and TAGM embolization agents are effective and safe modalities in treating patients with fibroids, with no significant variation of both agents in most outcomes.
摘要:
未经授权:通过比较疗效来确定首选药物,梗死程度,聚乙烯醇颗粒(PVA)和三丙烯酸明胶栓塞(TAGM)剂在子宫动脉栓塞中的副作用。
UNASSIGNED:我们收录了一些文章,比较了PVA和TAGM栓塞剂在子宫肌瘤治疗中的作用。主要结局包括子宫体积减少(%),优势肿瘤体积减少(%),纤维瘤梗死率,完全梗死纤维瘤,并发症,24小时后疼痛评分,手术时间(分钟),住院时间,透视时间(分钟),和症状严重程度评分的变化。
未经评估:本研究纳入了符合纳入标准的8篇文章。与TAGM相比,我们的分析得出PVA在头24小时内完全纤维瘤梗死率的总体优势。然而,TAGM优于PVA,梗死发生率<90%。虽然两种栓塞技术在症状严重程度评分变化方面表现出相似的效果,子宫体积减少的百分比,优势肿瘤体积减少的百分比,90-99%梗死率,在第一个24小时后评估的完全梗死率,第一个24小时后的疼痛评分,程序时间,透视时间,未成年人,和主要并发症。
UNASSIGNED:PVA和TAGM栓塞剂都是治疗肌瘤的有效和安全的方法,在大多数结果中,两种药物没有显著差异。
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