Abstract：
BACKGROUND: The underlying pathophysiological mechanisms of chronic Whiplash Associated Disorders (WAD) are not fully understood. More knowledge of morphology is needed to better understand the disorder, improve diagnostics and treatments. The aim was to investigate dorsal neck muscle volume (MV) and muscle fat infiltration (MFI) in relation to self-reported neck disability among 30 participants with chronic WAD grade II-III compared to 30 matched healthy controls.
METHODS: MV and MFI at spinal segments C4 through C7 in both sexes with mild- to moderate chronic WAD (n = 20), severe chronic WAD (n = 10), and age- and sex matched healthy controls (n = 30) was compared. Muscles: trapezius, splenius, semispinalis capitis and semispinalis cervicis were segmented by a blinded assessor and analyzed.
RESULTS: Higher MFI was found in right trapezius (p = 0.007, Cohen\'s d = 0.9) among participants with severe chronic WAD compared to healthy controls. No other significant difference was found for MFI (p = 0.22-0.95) or MV (p = 0.20-0.76).
CONCLUSIONS: There are quantifiable changes in muscle composition of right trapezius on the side of dominant pain and/or symptoms, among participants with severe chronic WAD. No other statistically significant differences were shown for MFI or MV. These findings add knowledge of the association between MFI, muscle size and self-reported neck disability in chronic WAD.
BACKGROUND: NA. This is a cross-sectional case-control embedded in a cohort study.
METHODS: MV and MFI at spinal segments C4 through C7 in both sexes with mild- to moderate chronic WAD (n = 20), severe chronic WAD (n = 10), and age- and sex matched healthy controls (n = 30) was compared. Muscles: trapezius, splenius, semispinalis capitis and semispinalis cervicis were segmented by a blinded assessor and analyzed.
RESULTS: Higher MFI was found in right trapezius (p = 0.007, Cohen\'s d = 0.9) among participants with severe chronic WAD compared to healthy controls. No other significant difference was found for MFI (p = 0.22-0.95) or MV (p = 0.20-0.76).
CONCLUSIONS: There are quantifiable changes in muscle composition of right trapezius on the side of dominant pain and/or symptoms, among participants with severe chronic WAD. No other statistically significant differences were shown for MFI or MV. These findings add knowledge of the association between MFI, muscle size and self-reported neck disability in chronic WAD.
BACKGROUND: NA. This is a cross-sectional case-control embedded in a cohort study.
摘要：
背景：慢性鞭打相关疾病（WAD）的潜在病理生理机制尚未完全了解。需要更多的形态学知识来更好地理解疾病，改善诊断和治疗。目的是调查30名患有II-III级慢性WAD的参与者与30名匹配的健康对照者相比，背颈肌肉体积（MV）和肌肉脂肪浸润（MFI）与自我报告的颈部残疾的关系。
方法：在轻度至中度慢性WAD（n=20）的两性脊柱C4至C7节段的MV和MFI，重度慢性WAD（n=10），并比较年龄和性别匹配的健康对照（n=30）。肌肉:斜方肌,脾,头半肌炎和宫颈半肌由盲法评估者进行分割和分析。
结果：在患有严重慢性WAD的参与者中，与健康对照组相比，在右斜方肌中发现了更高的MFI（p=0.007，Cohen'sd=0.9）。MFI（p=0.22-0.95）或MV（p=0.20-0.76）没有其他显着差异。
结论：在显性疼痛和/或症状的一侧，右斜方肌的肌肉成分有可量化的变化，在患有严重慢性WAD的参与者中。MFI或MV没有显示其他统计学上的显著差异。这些发现增加了对MFI，慢性WAD患者的肌肉大小和自我报告的颈部残疾。
背景：NA。这是一项纳入队列研究的横断面病例对照。
方法：在轻度至中度慢性WAD（n=20）的两性脊柱C4至C7节段的MV和MFI，重度慢性WAD（n=10），并比较年龄和性别匹配的健康对照（n=30）。肌肉:斜方肌,脾,头半肌炎和宫颈半肌由盲法评估者进行分割和分析。
结果：在患有严重慢性WAD的参与者中，与健康对照组相比，在右斜方肌中发现了更高的MFI（p=0.007，Cohen'sd=0.9）。MFI（p=0.22-0.95）或MV（p=0.20-0.76）没有其他显着差异。
结论：在显性疼痛和/或症状的一侧，右斜方肌的肌肉成分有可量化的变化，在患有严重慢性WAD的参与者中。MFI或MV没有显示其他统计学上的显著差异。这些发现增加了对MFI，慢性WAD患者的肌肉大小和自我报告的颈部残疾。
背景：NA。这是一项纳入队列研究的横断面病例对照。
