关键词: Array antenna Cone photoreceptor Dielectric Resonator Antenna (DRA) Electrochemical signals Outer segment mfERG

来  源:   DOI:10.1016/j.heliyon.2023.e13794   PDF(Pubmed)

Abstract:
The retina encompasses several cone and rod photoreceptors at fovea region i.e., 90 million cells of rod photoreceptors and 4.5million cells of cone photoreceptors. The overall photoreceptors determine the vision of every human. An electromagnetic dielectric resonator antenna has been presented for retina photoreceptors in order to model them at fovea and its peripheral retina with the respected angular spectrum. Three coloring primary system of human eye (R, G, B) can be realized based on the model. Three miscellaneous models i.e., simple, graphene coated, and interdigital models have been presented in this paper. The nonlinear property of interdigital structures is one of the best advantages to use for creating the capacitor. The capacitance property helps improving the upper band of visible spectrum. The absorption of light for graphene as an energy harvesting material and its conversion into electrochemical signals is making it one of the best models. The mentioned three electromagnetic models of human photoreceptors have been expressed as a receiver antenna. The proposed electromagnetic models based on dielectric resonator antenna (DRA) are being analyzed for cones and rods photoreceptors of retina in the human eye by Finite Integral Method (FIM) utilized by CST MWS. The results show that the models are so fine for vision spectrum due to its localized near field enhancement property. The results indicate fine parameters of S 11 (return loss below -10 dB) with invaluable resonants in a wide range of frequencies from 405 THz to 790 THz (vision spectrum), appropriate S 21 (insertion loss 3-dB bandwidth), very good field distribution of electric and magnetic fields for flowing the power and electrochemical signals. Finally, mfERG clinical and experimental results validate the numeric results by the normalized output to input ratio of these models and it points out that these models can stimulate the electrochemical signals in photoreceptor cells for the best suiting of realizing the new retinal implants.
摘要:
视网膜在中央凹区域包含几个视锥和视杆光感受器,即90万个视杆细胞和450万个视锥细胞。整体的光感受器决定了每个人的视力。已经提出了一种用于视网膜感光体的电磁介质谐振器天线,以便在中央凹及其周边视网膜处对它们进行建模,并具有相应的角谱。人眼的三种着色主系统(R,G,B)可以基于模型实现。三种杂项模型,即,简单,石墨烯涂层,本文提出了跨数字模型。叉指结构的非线性特性是用于创建电容器的最佳优点之一。电容特性有助于改善可见光谱的上波段。石墨烯作为能量收集材料的光吸收及其转化为电化学信号使其成为最佳模型之一。提到的人类光感受器的三个电磁模型已表示为接收器天线。通过CSTMWS使用的有限积分方法(FIM),正在分析基于介质谐振器天线(DRA)的拟议电磁模型,以分析人眼视网膜的视锥和视杆光感受器。结果表明,由于其局部近场增强特性,该模型对于视觉光谱非常好。结果表明,S11的精细参数(回波损耗低于-10dB)具有在405THz至790THz(视觉光谱)的宽频率范围内的宝贵共振,适当的S21(插入损耗3-dB带宽),非常好的电场和磁场的场分布流动的功率和电化学信号。最后,mfERG临床和实验结果通过这些模型的归一化输出与输入比验证了数值结果,并指出这些模型可以刺激感光细胞中的电化学信号,以最适合实现新的视网膜植入物。
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