Mesh : Male Humans Rubber Latex / adverse effects Interleukin-10 Interleukin-13 Interleukin-5 Latex Hypersensitivity / epidemiology Manufacturing Industry Immunoglobulin E

来  源:   DOI:10.1097/JOM.0000000000002830

Abstract:
To present study aimed to investigate the prevalence of latex sensitivity in a workplace that produced rubber-based vehicle seals.
The serum latex-specific IgE levels, respiratory complaints, PFT, serum interleukin (IL)-4, IL-5, IL-8, IL-10, IL-13 levels of all male workers (n = 108) exposed to latex in the workplace, which produced rubber seals, were compared with the control group (n = 52).
The rates of latex-specific IgE >0.10 kU/L in the workers and control group were 12.3% and 4.1%, respectively ( P = 0.147). There was no difference in IL-4, IL-5, IL-10, and IL-13 levels between latex-specific IgE-positive, and -negative participants.
Latex sensitivity was higher in workers who used rubber as a raw material than in the control group but it was not statistically significant.
摘要:
目的:本研究旨在调查生产基于橡胶的车辆密封件的工作场所中乳胶敏感性的患病率。
方法:血清乳胶特异性IgE水平,呼吸不适,PFT,血清白细胞介素(IL)-4,IL-5,IL-8,IL-10,IL-13水平的所有男性工人(n=108)在工作场所暴露于乳胶,生产橡胶密封件,与对照组(n=52)进行比较。
结果:工人和对照组的乳胶特异性IgE>0.10kU/L的比率分别为12.3%和4.1%,分别(p=0.147)。乳胶特异性IgE阳性和阴性参与者之间的IL-4,IL-5,IL-10和IL-13水平没有差异。
结论:使用橡胶作为原料的工人的胶乳敏感性高于对照组,但没有统计学意义。
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