Abstract：
Peripheral magnetic stimulation (PMS) is a potentially promising modality to help manage postoperative pain. We systematically reviewed the effect of PMS on acute and chronic postoperative pain. MEDLINE, Cochrane CENTRAL, EMBASE, ProQuest Dissertations, and clinical trials.gov were searched from inception until May 2021. We included studies of any study design that included patients ≥18 years of age undergoing any type of surgery that administered PMS within the perioperative period and evaluated postoperative pain. Seventeen randomized controlled trials and 1 nonrandomized clinical trial were included into the review. Thirteen out of the 18 studies found a positive effect with PMS on postoperative pain scores. In our meta-analysis, peripheral magnetic stimulation was more efficacious than sham or no intervention within the first 7 postoperative days (mean difference [MD] -1.64 on a 0 to 10 numerical rating score, 95% confidence interval [CI] -2.08 to -1.20, I2 = 77%, 6 studies, 231 patients). This was also true at 1 and 2 months after surgery (MD -1.82, 95% CI -2.48 to -1.17, I2 = 0%, 3 studies, 104 patients; and MD -1.96, 95% CI -3.67 to -.26, I2 = 84%, 3 studies, 104 patients, respectively). A difference was not seen with persistent pain at 6 and 12-months after surgery, acute postoperative opioid consumption, or adverse events between groups. Results are limited by heterogeneity and generally low-quality studies, as well as low or very low quality of evidence. High-quality and adequately blinded trials are needed to definitively confirm the benefits of peripheral magnetic stimulation administered in the perioperative period. PERSPECTIVE: This review evaluates the efficacy and safety of PMS on postoperative pain. The results help elucidate PMS\' role in postoperative pain management and identify gaps where more research is required.
摘要：
周围磁刺激是一种潜在的有前途的方式来帮助管理术后疼痛。我们系统综述了外周磁刺激对急性和慢性术后疼痛的影响。MEDLINE,科克伦中部,EMBASE,ProQuest论文,和ClinicalTrials.gov从一开始一直搜索到2021年5月。我们纳入了任何研究设计的研究，这些研究设计包括在围手术期接受外周磁刺激的年龄≥18岁的患者，并评估了术后疼痛。共纳入17项随机对照试验和1项非随机临床试验。18项研究中有13项发现外周磁刺激对术后疼痛评分有积极影响。在我们的荟萃分析中，在术后前7天内，外周磁刺激比假手术或无干预更有效（0-10数字评分的平均差[MD]-1.64，95%置信区间[CI]-2.08至-1.20，I2=77%，6项研究[231例患者])。手术后1个月和2个月也是如此(MD-1.82,95%CI-2.48至-1.17,I2=0%,3项研究[104例患者]；MD-1.96，95%CI-3.67至-0.26，I2=84%，3项研究[分别为104例患者]）。在手术后6个月和12个月的持续性疼痛没有观察到差异，术后急性阿片类药物消耗，或组间不良事件。结果受到异质性和通常低质量研究的限制，以及证据质量低或非常低。需要高质量和充分的盲化试验来明确确认围手术期外周磁刺激的益处。观点：本综述评估外周磁刺激（PMS）对术后疼痛的疗效和安全性。结果有助于阐明PMS在术后疼痛管理中的作用，并确定需要更多研究的差距。
