Abstract:
World Health Organization (WHO) reported that over 1.5 billion people are infected by soil-transmitted helminths (STH) worldwide in sub-Saharan Africa, the United States of America, China, and East Asia. Heavy infections and polyparasitism are associated with higher morbidity rates, and the patients are exposed to increased vulnerability to other diseases. Therefore, accurate diagnosis followed by mass treatment for morbidity control is necessary.STH diagnosis commonly involves the microscopic observation of the presence of the STH eggs and larvae in the faecal samples. Furthermore, molecular approaches are increasingly utilised in monitoring and surveillance as they show higher sensitivity. Their capability to differentiate hookworm species is an advantage over the Kato-Katz technique. This review discusses the advantages and limitations of microscopy and various molecular tools used for STH detection.
摘要:
世界卫生组织(WHO)报告说,在撒哈拉以南非洲,全世界有超过15亿人感染了土壤传播的蠕虫(STH)。美利坚合众国,中国,和东亚。重度感染和多寄生虫与较高的发病率相关,并且患者对其他疾病的脆弱性增加。因此,准确的诊断,然后进行大规模治疗以控制发病率是必要的。STH诊断通常涉及对粪便样品中STH卵和幼虫的存在进行显微镜观察。此外,分子方法越来越多地用于监测和监测,因为它们显示出更高的灵敏度。它们区分钩虫种类的能力是优于Kato-Katz技术的优势。这篇综述讨论了用于STH检测的显微镜和各种分子工具的优点和局限性。