PDF(Pubmed)
Abstract：
Introduction In this study, we planned to investigate the effect of hyperoxygenation on mortality and morbidity in patients with head trauma who were followed and treated in the intensive care unit (ICU). Methods Head trauma cases (n = 119) that were followed in the mixed ICU of a 50-bed tertiary care center in Istanbul between January 2018 and December 2019 were retrospectively analyzed for the negative effects of hyperoxia. Age, gender, height/weight, additional diseases, medications used, ICU indication, Glasgow Coma Scale score recorded during ICU follow-up, Acute Physiology and Chronic Health Evaluation (APACHE) II score, length of hospital/ICU stay, the presence of complications, number of reoperations, length of intubation, and the patient\'s discharge or death status were evaluated. The patients were divided into three groups according to the highest partial pressure of oxygen (PaO2) value (200 mmHg) in the arterial blood gas (ABG) taken on the first day of admission to the ICU, and ABGs on the day of ICU admission and discharge were compared. Results In comparison, the first arterial oxygen saturation and initial PaO2 mean values were found to be statistically significantly different. There was a statistically significant difference in mortality and reoperation rates between groups. The mortality was higher in groups 2 and 3, and the rate of reoperation was higher in group 1. Conclusion In our study, mortality was found to be high in groups 2 and 3, which we considered hyperoxic. In this study, we tried to draw attention to the negative effects of common and easily administered oxygen therapy on mortality and morbidity in ICU patients.
摘要：
引言在这项研究中，我们计划调查在重症监护病房(ICU)接受随访和治疗的头部外伤患者中,高氧对死亡率和发病率的影响.方法回顾性分析2018年1月至2019年12月在伊斯坦布尔一家拥有50张床位的三级护理中心的混合ICU中随访的头部外伤病例（n=119）的高氧负面影响。年龄,性别,身高/体重,其他疾病,使用的药物，ICU适应症,ICU随访期间记录的格拉斯哥昏迷量表评分，急性生理学和慢性健康评估（APACHE）II评分，住院/ICU住院时间，并发症的存在，重新操作的次数，插管长度,并评估患者的出院或死亡状况。根据入住ICU第一天的动脉血气(ABG)中的最高氧分压(PaO2)值(200mmHg)将患者分为三组,并比较ICU入院和出院当天的ABGs。结果相比较而言,发现第一动脉血氧饱和度和初始PaO2平均值在统计学上有显著差异.两组之间的死亡率和再手术率差异有统计学意义。第2组和第3组的死亡率较高，第1组的再手术率较高。结论在我们的研究中,我们认为第2组和第3组的死亡率较高.在这项研究中,我们试图引起人们对常用和易于使用的氧疗对ICU患者死亡率和发病率的负面影响的关注.
