PDF(Pubmed)
Abstract：
To compare the incidence and outcomes of congenital and neonatal varicella in Australia in the pre-vaccination (1995-1997) and post-vaccination era (after 2005 to November 2020), active prospective national surveillance for congenital varicella syndrome (CVS) and neonatal varicella infection (NVI) was conducted through the Australian Paediatric Surveillance Unit (APSU). Compared with 1995-1997, there was a 91.5% reduction in the incidence of CVS and a 91.3% reduction in the incidence of NVI in 2009-2020. However, almost half of the mothers in 2009-2020 were born overseas and came from countries without a vaccination program. Although there has been a substantial and sustained decrease in the reported incidence of CVS and NVI in Australia since 2006, congenital and neonatal varicella infections persist. Thus, there is an opportunity for targeted screening of varicella in young migrant, asylum seeker and refugee women at risk of varicella infection and prioritisation for vaccination to prevent CVS and NVI.
摘要：
比较澳大利亚在疫苗接种前（1995-1997年）和疫苗接种后（2005年至2020年11月）的先天性和新生儿水痘的发病率和结果，通过澳大利亚儿科监测单位(APSU)对先天性水痘综合征(CVS)和新生儿水痘感染(NVI)进行了积极的前瞻性国家监测.与1995-1997年相比，2009-2020年CVS发病率降低了91.5%，NVI发病率降低了91.3%。然而,2009-2020年，近一半的母亲出生在海外，来自没有疫苗接种计划的国家。尽管自2006年以来，澳大利亚报告的CVS和NVI发病率大幅持续下降，但先天性和新生儿水痘感染仍然存在。因此，有机会对年轻移民进行有针对性的水痘筛查，寻求庇护者和难民妇女面临水痘感染的风险，并优先接种疫苗以预防CVS和NVI。
