PDF(Pubmed)
Abstract：
UNASSIGNED: To figure out the difference of integrity of Gerota\'s fascia and perirenal fat between Retroperitoneal Laparoscopic Radical Nephrectomy (RLRN) and Transperitoneal Laparoscopic Radical Nephrectomy (TLRN).
UNASSIGNED: This is a prospective comparative study of patients with Renal Cell Carcinoma (RCC) from a designated tertiary center in Lanzhou, China. We have developed and propose a scoring tool to quantify the integrity of nephrectomy specimens from both approaches. The integrity score is based on 6 common conditions of nephrectomy specimens. Specimens are scored on a 1 to 6-point scale according to the integrity of Gerota\'s fascia and perirenal fat. We applied the integrity score to 142 consecutive patients. Integrity scores were compared between RLRN and TLRN groups. Factors associated with low integrity score were assessed by logistic regression.
UNASSIGNED: Among 142 patients, 79 (55.6%) patients and 63 (44.4%) patients, respectively, underwent RLRN and TLRN. There was a significant difference in the distribution of integrity score between the two groups (P < 0.001). RLRN (odds ratio 10.65, 95%CI 4.29-26.45, P < 0.001), tumor size (odds ratio 1.22, 95%CI 1.04-1.42, P = 0.015) and Body Mass Index (BMI) (odds ratio 0.83, 95%CI 0.72-0.96, P = 0.010) were significantly associated with low integrity score. The logistic regression equation showed good power to predict low integrity score.
UNASSIGNED: RLRN has poor integrity of Gerota\'s fascia and the perirenal fat. The integrity score can be used to evaluate the extent of resection and specimen completeness in LRN. Postoperative evaluation of the integrity score is of great value for urologists to evaluate the risk of tumor residue.
UNASSIGNED: This is a prospective comparative study of patients with Renal Cell Carcinoma (RCC) from a designated tertiary center in Lanzhou, China. We have developed and propose a scoring tool to quantify the integrity of nephrectomy specimens from both approaches. The integrity score is based on 6 common conditions of nephrectomy specimens. Specimens are scored on a 1 to 6-point scale according to the integrity of Gerota\'s fascia and perirenal fat. We applied the integrity score to 142 consecutive patients. Integrity scores were compared between RLRN and TLRN groups. Factors associated with low integrity score were assessed by logistic regression.
UNASSIGNED: Among 142 patients, 79 (55.6%) patients and 63 (44.4%) patients, respectively, underwent RLRN and TLRN. There was a significant difference in the distribution of integrity score between the two groups (P < 0.001). RLRN (odds ratio 10.65, 95%CI 4.29-26.45, P < 0.001), tumor size (odds ratio 1.22, 95%CI 1.04-1.42, P = 0.015) and Body Mass Index (BMI) (odds ratio 0.83, 95%CI 0.72-0.96, P = 0.010) were significantly associated with low integrity score. The logistic regression equation showed good power to predict low integrity score.
UNASSIGNED: RLRN has poor integrity of Gerota\'s fascia and the perirenal fat. The integrity score can be used to evaluate the extent of resection and specimen completeness in LRN. Postoperative evaluation of the integrity score is of great value for urologists to evaluate the risk of tumor residue.
摘要：
UNASSIGNED：目的了解腹膜后腹腔镜肾癌根治术（RLRN）和经腹膜腹腔镜肾癌根治术（TLRN）之间Gerota筋膜和肾周脂肪完整性的差异。
UNASSIGNED：这是一项来自兰州指定三级中心的肾细胞癌（RCC）患者的前瞻性比较研究，中国。我们已经开发并提出了一种评分工具来量化两种方法的肾切除术标本的完整性。完整性评分基于肾切除术标本的6种常见情况。根据Gerota筋膜和肾周脂肪的完整性，以1至6分制对样本进行评分。我们将完整性评分应用于142例连续患者。比较RLRN和TLRN组之间的完整性评分。通过逻辑回归评估与低完整性评分相关的因素。
未经证实：在142名患者中，79例（55.6%）患者和63例（44.4%）患者，分别,接受了RLRN和TLRN。两组患者的完整性评分分布差异有统计学意义(P<0.001)。RLRN（比值比10.65，95CI4.29-26.45，P<0.001），肿瘤大小(比值比1.22,95CI1.04-1.42,P=0.015)和体重指数(BMI)(比值比0.83,95CI0.72-0.96,P=0.010)与低完整性评分显著相关.逻辑回归方程显示出预测低完整性评分的良好能力。
UNASSIGNED：RLRN的Gerota筋膜和肾周脂肪的完整性较差。完整性评分可用于评估LRN中的切除程度和标本完整性。术后评价完整性评分对泌尿科医师评价肿瘤残留风险具有重要价值。
UNASSIGNED：这是一项来自兰州指定三级中心的肾细胞癌（RCC）患者的前瞻性比较研究，中国。我们已经开发并提出了一种评分工具来量化两种方法的肾切除术标本的完整性。完整性评分基于肾切除术标本的6种常见情况。根据Gerota筋膜和肾周脂肪的完整性，以1至6分制对样本进行评分。我们将完整性评分应用于142例连续患者。比较RLRN和TLRN组之间的完整性评分。通过逻辑回归评估与低完整性评分相关的因素。
未经证实：在142名患者中，79例（55.6%）患者和63例（44.4%）患者，分别,接受了RLRN和TLRN。两组患者的完整性评分分布差异有统计学意义(P<0.001)。RLRN（比值比10.65，95CI4.29-26.45，P<0.001），肿瘤大小(比值比1.22,95CI1.04-1.42,P=0.015)和体重指数(BMI)(比值比0.83,95CI0.72-0.96,P=0.010)与低完整性评分显著相关.逻辑回归方程显示出预测低完整性评分的良好能力。
UNASSIGNED：RLRN的Gerota筋膜和肾周脂肪的完整性较差。完整性评分可用于评估LRN中的切除程度和标本完整性。术后评价完整性评分对泌尿科医师评价肿瘤残留风险具有重要价值。
