PDF(Pubmed)
Abstract：
Solar ultraviolet radiation (UVR) is the most significant occupational carcinogenic exposure in terms of the number of workers exposed (i.e., outdoor workers). Consequently, solar UVR-induced skin cancers are among the most common forms of occupational malignancies that are potentially expected globally. This systematic review is registered in PROSPERO (CRD42021295221) and aims to assess the risk of cutaneous squamous cell carcinoma (cSCC) associated to occupational solar UVR exposure. Systematic searches will be performed in three electronic literature databases (PubMed/Medline, EMBASE, and Scopus). Further references will be retrieved by a manual search (e.g., in grey literature databases, internet search engines, and organizational websites). We will include cohort studies and case-control studies. Risk of Bias assessment will be conducted separately for case-control and cohort studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) will be used for the certainty of assessment. In case quantitative pooling is not feasible, a narrative synthesis of results will be performed.
摘要：
太阳紫外线辐射（UVR）是以暴露工人数量而言最重要的职业致癌暴露（即，户外工作者)。因此,太阳能UVR诱导的皮肤癌是全球潜在的最常见的职业恶性肿瘤之一。该系统评价在PROSPERO（CRD42021295221）中注册，旨在评估与职业性日光UVR暴露相关的皮肤鳞状细胞癌（cSCC）的风险。系统搜索将在三个电子文献数据库(PubMed/Medline，EMBASE,和Scopus）。进一步的参考文献将通过手动搜索来检索(例如，在灰色文献数据库中，互联网搜索引擎,和组织网站)。我们将包括队列研究和病例对照研究。偏差风险评估将分别进行病例对照和队列研究。建议评估的分级，发展,和评估(等级)将用于评估的确定性。如果定量汇集不可行，将进行结果的叙述性综合。
