PDF(Pubmed)
Abstract：
UNASSIGNED: Organophosphorus (OP) pesticides are extensively used both in developed and developing countries. Organophosphorus poisoning primarily occurs through occupational, accidental, and suicidal exposures. Toxicity through parenteral injections is seldom reported and there are only very few case reports till date.
UNASSIGNED: We report a case of parenteral injection of 10 mL of OP compound (Dichlorvos 76%) into a swelling over the left leg. The compound was injected by the patient himself as adjuvant therapy for swelling. Initial manifestations included vomiting, abdomen pain, and excessive secretions followed by neuromuscular weakness. The patient was subsequently intubated and treated with atropine and pralidoxime. The patient did not improve with antidotes for OP poisoning, attributed to the depot the OP compound had formed. The swelling was excised and the patient immediately showed response to the treatment. Biopsy of the swelling showed granuloma and fungal hyphae. The patient developed intermediate syndrome during the ICU stay and was discharged after 20 days of hospital stay.
UNASSIGNED: Jacob J, Reddy CHK, James J. \"The Toxic Depot\": Parenteral Insecticide Injection. Indian J Crit Care Med 2022;26(7):877-878.
UNASSIGNED: We report a case of parenteral injection of 10 mL of OP compound (Dichlorvos 76%) into a swelling over the left leg. The compound was injected by the patient himself as adjuvant therapy for swelling. Initial manifestations included vomiting, abdomen pain, and excessive secretions followed by neuromuscular weakness. The patient was subsequently intubated and treated with atropine and pralidoxime. The patient did not improve with antidotes for OP poisoning, attributed to the depot the OP compound had formed. The swelling was excised and the patient immediately showed response to the treatment. Biopsy of the swelling showed granuloma and fungal hyphae. The patient developed intermediate syndrome during the ICU stay and was discharged after 20 days of hospital stay.
UNASSIGNED: Jacob J, Reddy CHK, James J. \"The Toxic Depot\": Parenteral Insecticide Injection. Indian J Crit Care Med 2022;26(7):877-878.
摘要：
未经评估：有机磷（OP）农药在发达国家和发展中国家都被广泛使用。有机磷中毒主要发生在职业性、意外,和自杀暴露。很少报道通过肠胃外注射的毒性，迄今为止只有很少的病例报告。
未经证实：我们报告了一例肠胃外注射10mLOP化合物（敌敌畏76％）进入左腿肿胀的病例。该化合物由患者自己注射作为肿胀的辅助疗法。最初的表现包括呕吐,腹痛,分泌过多，然后是神经肌肉无力。随后对患者进行了插管，并用阿托品和普利肟治疗。患者使用解毒剂治疗OP中毒没有改善，归因于OP化合物形成的储库。切除肿胀,患者立即显示对治疗的反应。肿胀活检显示肉芽肿和真菌菌丝。患者在ICU住院期间出现中间综合征，住院20天后出院。
未经批准：JacobJ,ReddyCHK,JamesJ.“有毒仓库”：肠胃外杀虫剂注射液。印度JCritCareMed2022；26（7）：877-878。
未经证实：我们报告了一例肠胃外注射10mLOP化合物（敌敌畏76％）进入左腿肿胀的病例。该化合物由患者自己注射作为肿胀的辅助疗法。最初的表现包括呕吐,腹痛,分泌过多，然后是神经肌肉无力。随后对患者进行了插管，并用阿托品和普利肟治疗。患者使用解毒剂治疗OP中毒没有改善，归因于OP化合物形成的储库。切除肿胀,患者立即显示对治疗的反应。肿胀活检显示肉芽肿和真菌菌丝。患者在ICU住院期间出现中间综合征，住院20天后出院。
未经批准：JacobJ,ReddyCHK,JamesJ.“有毒仓库”：肠胃外杀虫剂注射液。印度JCritCareMed2022；26（7）：877-878。
