关键词: Brucella infection diagnosis and treatment immune-mediated nature neuralgic amyotrophy

来  源:   DOI:10.2147/IDR.S400228   PDF(Pubmed)

Abstract:
Multiple micro-organisms associated with Neuralgic Amyotrophy (NA) have been reported and Brucella species should be an important and overlooked infectious cause or trigger.We report a rare case of neuralgic amyotrophy associated with Brucella infection and is believed to be the first such case report in China. A 42-year-old male with brucellosis was confirmed serologically, who presented recurrent fever and fatigue and suddenly developed severe pain in the right shoulder within one week, followed by the inability to lift and abduct the proximal end of the right upper limb. Based on typical clinical manifestions, MRI neuroimaging of the brachial plexus and neuro-electrophysiological studies to confirm a diagnosis of NA and presented spontaneous recovery during this period, immunomodulatory treatment with corticosteroid or intravenous immunoglobulin had not been attempted, leaving a serious movement disorder in the right upper limb. Even rare, NA and other neurobrucellosis forms should be considered as complications of Brucella infection.
摘要:
已经报道了与神经能肌萎缩症(NA)相关的多种微生物,布鲁氏菌应该是重要且被忽视的感染原因或触发因素。我们报告了一例罕见的与布鲁氏菌感染相关的神经能性肌萎缩病例,据信是中国首例此类病例报告。一名42岁男性布鲁氏菌病血清学证实,反复发烧和疲劳,一周内右肩突然出现剧烈疼痛,其次是无法抬起和绑架右上肢的近端。根据典型的临床表现,臂丛神经的MRI神经成像和神经电生理研究,以确认NA的诊断,并在此期间呈现自发恢复,尚未尝试使用皮质类固醇或静脉注射免疫球蛋白进行免疫调节治疗,在右上肢留下严重的运动障碍。甚至罕见,NA和其他神经布鲁氏菌病形式应被视为布鲁氏菌感染的并发症。
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