Abstract：
UNASSIGNED: Systemic autoimmune rheumatic diseases can occur as paraneoplastic phenomena in the context of underlying malignancies. We present three illustrative clinical cases and a narrative literature review focusing on systemic sclerosis, dermatomyositis and palmar fasciitis and polyarthritis syndrome.
UNASSIGNED: Medical data of three patients from the University Hospitals Leuven were retrospectively and anonymously obtained and reviewed. A narrative review was performed, searching the databases of PubMed, Embase and Cochrane Library.
UNASSIGNED: Systemic sclerosis, dermatomyositis and palmar fasciitis and polyarthritis syndrome are systemic autoimmune rheumatic diseases that can present as paraneoplastic phenomena. Systemic autoimmune rheumatic diseases are often associated with the presence of specific autoantibodies, some associated with a high likelihood of underlying malignancy. The presence of anti-ribonucleic acid polymerase III antibodies and anti-transcription intermediary factor 1 gamma antibodies indicates an increased risk of underlying cancer in systemic sclerosis and dermatomyositis, respectively. Individual patient prognosis can be improved through early detection of underlying malignancy, hence the importance of adequate cancer screening.
UNASSIGNED: Some systemic autoimmune rheumatic diseases can appear as paraneoplastic phenomena, whereby the presence of specific autoantibodies is known to be related to the likelihood of underlying malignancy. We highlight the importance of clinician\'s knowledge of these distinct features, as it facilitates early detection and treatment of underlying malignancy, thereby improving individual patient prognosis.
UNASSIGNED: Medical data of three patients from the University Hospitals Leuven were retrospectively and anonymously obtained and reviewed. A narrative review was performed, searching the databases of PubMed, Embase and Cochrane Library.
UNASSIGNED: Systemic sclerosis, dermatomyositis and palmar fasciitis and polyarthritis syndrome are systemic autoimmune rheumatic diseases that can present as paraneoplastic phenomena. Systemic autoimmune rheumatic diseases are often associated with the presence of specific autoantibodies, some associated with a high likelihood of underlying malignancy. The presence of anti-ribonucleic acid polymerase III antibodies and anti-transcription intermediary factor 1 gamma antibodies indicates an increased risk of underlying cancer in systemic sclerosis and dermatomyositis, respectively. Individual patient prognosis can be improved through early detection of underlying malignancy, hence the importance of adequate cancer screening.
UNASSIGNED: Some systemic autoimmune rheumatic diseases can appear as paraneoplastic phenomena, whereby the presence of specific autoantibodies is known to be related to the likelihood of underlying malignancy. We highlight the importance of clinician\'s knowledge of these distinct features, as it facilitates early detection and treatment of underlying malignancy, thereby improving individual patient prognosis.
摘要：
未经证实：全身性自身免疫性风湿性疾病可在潜在恶性肿瘤的背景下作为副肿瘤现象发生。我们提出了三个说明性的临床病例和一个叙述性文献综述，重点是系统性硬化症。皮肌炎和手掌筋膜炎和多关节炎综合征。
UNASSIGNED：回顾性地、匿名地获取并审查了来自鲁汶大学医院的三名患者的医学数据。进行了叙述性审查，搜索PubMed的数据库，Embase和Cochrane图书馆。
未经证实：系统性硬化症，皮肌炎和手掌筋膜炎和多关节炎综合征是全身性自身免疫性风湿性疾病，可表现为副肿瘤现象。系统性自身免疫性风湿病通常与特异性自身抗体的存在有关，一些与潜在恶性肿瘤的可能性很高有关。抗核糖核酸聚合酶III抗体和抗转录中间因子1γ抗体的存在表明系统性硬化症和皮肌炎中潜在癌症的风险增加，分别。通过早期发现潜在的恶性肿瘤可以改善个体患者的预后，因此，充分的癌症筛查的重要性。
未经证实：一些全身性自身免疫性风湿性疾病可以表现为副肿瘤现象，由此已知特异性自身抗体的存在与潜在恶性肿瘤的可能性有关。我们强调临床医生对这些不同特征的知识的重要性，因为它有助于早期发现和治疗潜在的恶性肿瘤，从而改善个体患者的预后。
UNASSIGNED：回顾性地、匿名地获取并审查了来自鲁汶大学医院的三名患者的医学数据。
未经证实：系统性硬化症，
未经证实：一些全身性自身免疫性风湿性疾病可以表现为副肿瘤现象，
