PDF(Pubmed)
Abstract：
Small ovarian fibromas (< 10cm) associated with elevated serum CA125 levels are rarely encountered, particularly in women of reproductive age. We report a rare case diagnosed in a 35-year-old patient after adnexectomy for a solid ovarian mass of approximately 5cm in maximum diameter, accompanied by elevated serum CA125 levels. In preoperative evaluation, no signs of inflammation from the genital tract were found, and no medical history of endometriosis, uterine leiomyomas, or non-gynecological cancer was reported. Intraoperative frozen section biopsy of surgical specimen obtained from the ovarian tumor had negative evaluation for malignancy. Histological examination of the surgical specimen confirmed the diagnosis of ovarian fibroma. The postoperative course was uneventful. Two months after surgery, the blood serum CA125 levels were within normal ranges. The patient is assessed at regular intervals in the gynecology outpatient clinic. In this paper, based on the data of the modern literature, a brief review of this rare nosological entity is made.
摘要：
很少遇到与血清CA125水平升高相关的小卵巢纤维瘤（<10cm），特别是在育龄妇女中。我们报告了一例罕见病例，在附件切除术后诊断为35岁的患者，其最大直径为约5cm的实性卵巢肿块。伴有血清CA125水平升高。在术前评估中，没有发现生殖道发炎的迹象，无子宫内膜异位症病史,子宫平滑肌瘤,报告了非妇科癌症。从卵巢肿瘤获得的手术标本的术中冰冻切片活检对恶性肿瘤的评估为阴性。手术标本的组织学检查证实了卵巢纤维瘤的诊断。术后病程顺利。手术后两个月,血清CA125水平在正常范围内.在妇科门诊定期对患者进行评估。在本文中,根据现代文学的数据，对这种罕见的nosological实体进行了简要回顾。
