Abstract：
From wild dogs (Lycaon pictus) in the Serengeti to tigers (Panthera tigris altaica) in the Russian Far East, canine distemper virus (CDV) has been repeatedly identified as a threat to wild carnivores. Between 2020 and 2022, six Indian leopards (P. pardus fusca) presented to Nepali authorities with fatal neurological disease, consistent with CDV. Here, we report the findings of a serosurvey of wild felids from Nepal. A total of 48 serum samples were tested, comprising 28 Bengal tigers (P. t. tigris) and 20 Indian leopards. Neutralizing antibodies were identified in three tigers and six leopards, equating to seroprevalences of 11% (CI: 2.8-29.3%, n = 28) and 30% (CI: 12.8-54.3%, n = 20), respectively. More than one-third of seropositive animals were symptomatic, and three died within a week of being sampled. The predation of domestic dogs (Canis lupus familiaris) has been posited as a potential route of infection. A comparison of existing diet studies revealed that while leopards in Nepal frequently predate on dogs, tigers do not, potentially supporting this hypothesis. However, further work, including molecular analyses, would be needed to confirm this.
摘要：
从塞伦盖蒂的野狗（Lycaonpictus）到俄罗斯远东地区的老虎（Pantheratigrisaltaica），犬瘟热病毒（CDV）已被多次确定为对野生食肉动物的威胁。从2020年到2022年，六只印度豹(P.pardusfusca）向尼泊尔当局提交了致命的神经系统疾病，与CDV一致。这里,我们报告了对尼泊尔野生猫科动物的血清调查结果。共检测了48份血清样本,包括28只孟加拉虎(P.t.Tigris）和20只印度豹。在三只老虎和六只豹子中鉴定了中和抗体，相当于11%的血清阳性率(CI：2.8-29.3%，n=28）和30%（CI：12.8-54.3%，n=20),分别。超过三分之一的血清反应阳性动物有症状，三个人在取样后一周内死亡。家犬（犬狼疮）的捕食已被认为是潜在的感染途径。对现有饮食研究的比较表明，尽管尼泊尔的豹子经常早于狗，老虎不，可能支持这一假设。然而,进一步的工作,包括分子分析，需要证实这一点。
