Abstract:
Ganoderma lucidum has long been used as a multi-purpose plant and functional food. The pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and triterpenoids. Ganoderic and lucidenic acids are the two major triterpenoids groups in G. lucidum. Despite the discovery of 22 types of lucidenic acids, research on lucidenic acids is significantly less extensive compared to that on ganoderic acid. To the best of our knowledge, for the first time, in this review, we aimed to summarize the sources, contents, chemical structures, and pharmacological effects, including anti-cancer, anti-inflammatory, antioxidant, anti-viral, neuroprotective, anti-hyperlipidemic, anti-hypercholesterolemic, and anti-diabetic properties, of lucidenic acids. Studies on lucidenic acids are still preliminary and have several limitations. Therefore, more in-depth studies with optimal designs are essential for the development of lucidenic acids as medicines, functional foods, and nutraceuticals.
摘要:
灵芝长期以来被用作多用途植物和功能性食品。灵芝的药理学性质主要归因于其多糖和三萜类。灵芝酸和Lucidenic酸是灵芝中的两个主要三萜类基团。尽管发现了22种Lucidenic酸,与灵芝酸相比,对Lucidenic酸的研究明显较少。据我们所知,第一次,在这次审查中,我们旨在总结来源,内容,化学结构,和药理作用,包括抗癌,抗炎,抗氧化剂,抗病毒,神经保护,抗高脂血症,抗高胆固醇血症,和抗糖尿病特性,Lucidenicacids.对Lucidenic酸的研究仍然是初步的,并且有一些局限性。因此,优化设计的更深入的研究对于开发作为药物的Lucidenic酸至关重要,功能性食品,和营养食品。